TY - JOUR A1 - Tugcu, Betul A1 - Acar, Nur A1 - Coskun, Cigdem A1 - Celik, Selda A1 - Yigit, Fadime T1 - Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome Y1 - 2014/5/1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 642 EP - 644 VL - 62 IS - 5 UR - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2014;volume=62;issue=5;spage=642;epage=644;aulast=Tugcu DO - 10.4103/0301-4738.109535 N2 - Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by vascular thrombosis or pregnancy morbidity. Ocular involvement in APS includes a broad spectrum of manifestations involving anterior and posterior segment or the presence of neuroophthalmologic features. Nonarteritic anterior ischemic optic neuropathy (NAION) is a very rare finding, and in this report a case having NAION as the prevailing sign of APS is presented. A middle-aged women who presented with visual disturbances in her left eye (LE) and turned out to have the diagnosis of primary APS with the help of rheumatological investigations is discussed. She was treated with oral steroids for NAION in her LE. With systemic and rheumatological work-up, primary APS was diagnosed, and hydroxychloroquine, coumadin, and aspirin were started, after which she remained stable under control. Due to the important diagnostic and therapeutic implications of APS, it should be considered in the differential diagnosis of NAION, particularly when the etiology is uncertain. ER -