author = {Lu, Yan. and Grisolia, Ana. and Ge, Yi-Rui. and Xue, Chun-Yan. and Cao, Qian. and Yang, Li-Ping. and Huang, Zhen-Ping.}, title = {{Comparison of femtosecond laser-assisted descemetic and predescemetic lamellar keratoplasty for keratoconus}}, journal ={Indian Journal of Ophthalmology}, volume ={65}, number ={1}, pages = {19-23}, doi = {10.4103/ijo.IJO_688_16}, year = {2017}, abstract ={Purpose: The purpose of this study is to compare the outcomes following femtosecond laser-assisted deep anterior lamellar keratoplasty (DALK) with 75% of stromal dissection (predescemetic group) and femtosecond laser-assisted DALK using big-bubble technique with total stromal resection (descemetic group) for the treatment of keratoconus. Subjects and Methods: Twenty eyes of 17 patients with keratoconus were studied. There were 10 eyes of 9 patients in predescemetic group and 10 eyes of 8 patients in descemetic group. The postoperative best-corrected visual acuity (BCVA), manifest refraction, keratometry, endothelial cell density (ECD), and central corneal thickness (CCT) were analyzed. Results: All surgeries were performed uneventfully. At 1 year after surgery, the BCVA, corneal astigmatism, keratometry, CCT, and ECD between two groups were not statistically significant (all P > 0.05). However, the mean manifest refraction was −9.43 ± 7.44 diopter (D) and −1.03 ± 1.13D in predescemetic and descemetic groups, respectively, which was statistically significant between two groups (P < 0.05). Conclusions: The results of BCVA and corneal astigmatism, keratometry, ECD, and CCT were comparable between two groups. However, the mean postoperative manifest refraction was lower in descemetic group.}, URL ={https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2017;volume=65;issue=1;spage=19;epage=23;aulast=Lu;t=6}, eprint ={https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2017;volume=65;issue=1;spage=19;epage=23;aulast=Lu;t=6} }