RT - Journal TY - JOUR A1 - Pradeep, Suchitra A1 - Thatikonda, Divya A1 - Nair, Nivedita A1 - Sudharshan, S A1 - Rao, Chetan A1 - Biswas, Jyotirmay T1 - Tubercular panophthalmitis in a patient with human immunodeficiency virus infection: Proven clinicopathologically and by molecular diagnostic tests YR - 2020/9/1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 2045 OP - 2047 VO - 68 IS - 9 UL - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=2045;epage=2047;aulast=Pradeep;t=5 DO - 10.4103/ijo.IJO_1190_20 N2 - Ocular tuberculosis (OTB) in patients with human immunodeficiency virus (HIV) commonly presents as choroidal tubercles or granuloma. We report a rare presentation of OTB with hypopyon granulomatous uveitis in a patient with HIV on highly active antiretroviral therapy (HAART). Aqueous humor polymerase chain reaction (PCR) was positive for Mycobacterium tuberculosis (MTB). Antitubercular therapy (ATT) was initiated despite which it progressed to scleral abscess and panophthalmitis. Enucleation with ball implantation was done. Histopathology revealed caseating granuloma with numerous acid-fast bacilli (AFB) and real-time PCR showed increased copies of MTB genome. After a full course of ATT, he had stable ocular and systemic condition at final follow-up. ER -