TY - JOUR A1 - Senthil, Sirisha A1 - Dada, Tanuj A1 - Das, Taraprasad A1 - Kaushik, Sushmita A1 - Puthuran, George A1 - Philip, Reni A1 - Rani, Padmaja A1 - Rao, Harsha A1 - Singla, Shaveta A1 - Vijaya, Lingam T1 - Neovascular glaucoma - A review Y1 - 2021/3/1 JF - Indian Journal of Ophthalmology JO - Indian J Ophthalmol SP - 525 EP - 534 VL - 69 IS - 3 UR - https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2021;volume=69;issue=3;spage=525;epage=534;aulast=Senthil DO - 10.4103/ijo.IJO_1591_20 N2 - Neovascular glaucoma (NVG) is a sight-threatening secondary glaucoma characterized by appearance of new vessels over the iris and proliferation of fibrovascular tissue in the anterior chamber angle. Retinal ischemia is the common driving factor and common causes are central retinal vein occlusion, proliferative diabetic retinopathy, and ocular ischemic syndrome. The current rise in the prevalence of NVG is partly related to increase in people with diabetes. A high index of suspicion and a thorough anterior segment evaluation to identify the early new vessels on the iris surface or angle are essential for early diagnosis of NVG. With newer imaging modalities such as the optical coherence tomography angiography and newer treatment options such as the anti-vascular endothelial growth factor, it is possible to detect retinal ischemia early, tailor appropriate treatment, monitor disease progression, and treatment response. The management strategies are aimed at reducing the posterior segment ischemia, reduce the neovascular drive, and control the elevated intraocular pressure. This review summarizes the causes, pathogenesis, and differential diagnoses of NVG, and the management guidelines. We also propose a treatment algorithm of neovascular glaucoma. ER -