Year : 1975 | Volume
: 23 | Issue : 3 | Page : 33--34
Basal cell carcinoma of conjunctiva
PV Apte1, VH Talib1, SD Patil2,
1 Department of Ophthalmology, Medical College, Aurangabad, (Maharashtra), India
2 Department of Pathology, Medical College, Aurangabad, (Maharashtra), India
V H Talib
Department of Pathology, Medical College, Aurangabad, (Maharashtra)
|How to cite this article:|
Apte P V, Talib V H, Patil S D. Basal cell carcinoma of conjunctiva.Indian J Ophthalmol 1975;23:33-34
|How to cite this URL:|
Apte P V, Talib V H, Patil S D. Basal cell carcinoma of conjunctiva. Indian J Ophthalmol [serial online] 1975 [cited 2022 Oct 5 ];23:33-34
Available from: https://www.ijo.in/text.asp?1975/23/3/33/31310
Carcinoma of the conjunctiva is rare. When conjunctiva is affected by carcinoma, the squamous cell type is at least ten times more common than the basal cell type  . Basal cell carcinoma of the conjunctiva is extermely rare. 
Because of its extreme rarity and certain unusal finding the present case is being reported.
A 69 year old female from Marathwada region was admitted to eye ward, Medical College Hospital, Aurangabad with a complaint of swelling of right upper lid. She has been suffering from swelling since 6 months. It was situated nasally in the palpabral aperture between the limbus and the plica. The lesion was fleshy, pedunculated, 2" x 1½" in size, mobile, and lobulated surface with irregular margin.
Growth was excised along full thickness of upper lid and gap was repaired by a full thickness pedicle graft from lower lid. Pedicle was cut after 3 weeks. Till to date there is no recurrance.
Histologically the lesion was composed of masses of various sizes and shapes embedded in the subconjunctival tissue. Some of the masses showed continuity with the surface epithelium [Figure 1]. Most of the areas showed interlacing strands of basal cells surrounding islands of connective tissue. The large masses were made up of nests of closely packed cells of uniform size [Figure 2] and oval shape with dark nuclei separated by a small amount of spineless cytoplasm. The peripheral cell layer of the tumour masses showed palisade arrangement [Figure 3], whereas the nuclei of the cells inside showed haphazard fashion.
Basal cell carcinoma of the conjunctiva is extermely rare. The lesion reported here is of interest in that it was of the basal cell type of carcinoma (undifferentiated), and was pedunculated rather than flat, suggesting that it had possibly developed in a, pre existing papilloma. It may arise from pre-existing leukoplakia, intraepithelial epithelioma (Bowen's disease), papilloma, or spontaneously after metaplasia of an area of conjunctival epithelium  . Although its site of predilection is the limbus, with extension to the cornea and the adjacent bulbar conjunctiva  . its primary site may also be the bulbar or palpabral. Commonly there is initial dyskeratotic change in the epithelium and this may be present microscopically in area surrounding the macroscopic lesion. The lesion itself tends to be flat and spreading, and may invade the cornea or sclera. The site of carcinoma, the age and sex of the patient are typical of the condition ,,.
A rare case of basal cell carcinoma of the with unusal finding is reported, conjunctiva.
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|4||Reese, A.B., 1956, Tumours of the eye and adenexa. Sec X-Fasciele 38. Armed forces Institute of Pathology, Washington 11.|
|5||Reese, A B., 1963, Tumours of the Eye, 2nd Ed., Harper and Row, New York, Evanston, and London. 23.|