Indian Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 1991  |  Volume : 39  |  Issue : 4  |  Page : 148--150

Clinico-biochemical study of experimental complicated cataracts


R Sihota, Madan Mohan, SK Angra, RL Mathur 
 Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All Institute of Medical Sciences, New Delhi 110 029, India

Correspondence Address:
R Sihota
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All Institute of Medical Sciences, New Delhi 110 029
India

Clinically observed complicated cataracts, generally do not have a definite causal factor. We studied the effects of E. coli toxin injected suprachoroidally, to simulate the effect of toxins released by extraocular organisms on the lens. 79.2% of eyes had a definable cataract at the end of the 6th week of observation. The biochemical changes portrayed an increased oxidative activity in the lens, evidenced by a fall in glutathione concentration, and the consequent tertiary reorientation of proteins to increase insoluble proteins, forming a cataract.


How to cite this article:
Sihota R, Mohan M, Angra S K, Mathur R L. Clinico-biochemical study of experimental complicated cataracts.Indian J Ophthalmol 1991;39:148-150


How to cite this URL:
Sihota R, Mohan M, Angra S K, Mathur R L. Clinico-biochemical study of experimental complicated cataracts. Indian J Ophthalmol [serial online] 1991 [cited 2022 Dec 2 ];39:148-150
Available from: https://www.ijo.in/article.asp?issn=0301-4738;year=1991;volume=39;issue=4;spage=148;epage=150;aulast=Sihota;type=0