ORIGINAL ARTICLE
Year : 1991 | Volume
: 39 | Issue : 4 | Page : 174--175
Anti-insulin antibodies and retinopathy in juvenile onset type-1 diabetes
K Sharma, PK Khosla, HK Tiwari, RK Sharma, JS Bajaj Dr. Rajendra Prasad Centre for Ophthalmic Sciences, Department of Medicine, Department of Anatomy, All Institute of Medical Sciences, New Delhi, India
Correspondence Address:
K Sharma Department of Neuro-Ophthalmology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Post Box 375, Lucknow - 226001 India
Juvenile diabetics have severe loss of beta cell function and require replacement therapy with insulin. Insulin antigenicity can produce anti-insulin antibodies resulting in allergic reactions and insulin resistance. The role of insulin-anti-insulin antibody complexes in the development and progress of chronic diabetic complications like microangiopathy is not very clear. In the present study, there was statistically a significant trend of higher insulin antibody binding levels in IDDM patients who developed retinopathy. Though there was a trend of higher insulin antibody in IDDM patients with retinopathy, there was no association between insulin antibody and HLA antigen which some authors have reported.
How to cite this article:
Sharma K, Khosla P K, Tiwari H K, Sharma R K, Bajaj J S. Anti-insulin antibodies and retinopathy in juvenile onset type-1 diabetes.Indian J Ophthalmol 1991;39:174-175
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How to cite this URL:
Sharma K, Khosla P K, Tiwari H K, Sharma R K, Bajaj J S. Anti-insulin antibodies and retinopathy in juvenile onset type-1 diabetes. Indian J Ophthalmol [serial online] 1991 [cited 2024 Mar 29 ];39:174-175
Available from: https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=1991;volume=39;issue=4;spage=174;epage=175;aulast=Sharma;type=0 |
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