Indian Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 1996  |  Volume : 44  |  Issue : 2  |  Page : 77--82

Retinitis pigmentosa genetics: A study in Indian population


Manisha S Vinchurkar1, Sudhakar M Sathye2, Madhurima Dikshit1 
1 Division of Biochemistry, University of Poona, Pune, India
2 Sathye Eye Hospital, Narayana Peth, Pune, India

Correspondence Address:
Manisha S Vinchurkar
Division of Biochemistry, University of Poona, Pune
India

A total of 151 retinitis pigmentosa (RP) patients from 83 families were screened and the frequencies of different genetic categories studied. One hundred and ten patients out of 151 had a positive inheritance pattern, and autosomal recessive (AR) emerged as the predominant (53 out of 151), genetic pattern followed by isolated or sporadic (41 out of 151) cases. Further study of autosomal recessive cases revealed consanguinity as the main characteristic (49 out of 53) in the Indian population studied. Early onset and severe progression of disease was seen in the consanguineous group.


How to cite this article:
Vinchurkar MS, Sathye SM, Dikshit M. Retinitis pigmentosa genetics: A study in Indian population.Indian J Ophthalmol 1996;44:77-82


How to cite this URL:
Vinchurkar MS, Sathye SM, Dikshit M. Retinitis pigmentosa genetics: A study in Indian population. Indian J Ophthalmol [serial online] 1996 [cited 2024 Mar 29 ];44:77-82
Available from: https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=1996;volume=44;issue=2;spage=77;epage=82;aulast=Vinchurkar;type=0