BRIEF COMMUNICATION
Year : 2008 | Volume
: 56 | Issue : 5 | Page : 430--434
Familial unilateral Brown syndrome
Nihal Kenawy1, Daniela T Pilz2, Patrick Watts3 1 St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, L7 8XP, United Kingdom 2 Institute of Medical Genetics, University Hospital of Wales, Cardiff, CF14 4XW, United Kingdom 3 Department of Ophthalmology, University Hospital of Wales, Cardiff, CF14 4XW, United Kingdom
Correspondence Address:
Patrick Watts University Hospital of Wales, Heath Park, Cardiff, CF14 4XW United Kingdom
We present a two-generation family with Brown syndrome. The proband was a six and a half-year-old female who presented with a history of failure of dextro-elevation of her left eye. A full ophthalmic evaluation was consistent with a left Brown syndrome. Family history revealed that her mother was operated on as a child for left Brown syndrome and examination of her four and a half-year-old sibling showed similar affection in the left eye. Autosomal dominant inheritance has been postulated in this condition. To our knowledge this is the first report of three members of a two-generation family with left-sided Brown syndrome. Genetic counseling of Brown syndrome cases is advised; nevertheless, identification of the responsible gene should shed more light on its genetics.
How to cite this article:
Kenawy N, Pilz DT, Watts P. Familial unilateral Brown syndrome.Indian J Ophthalmol 2008;56:430-434
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How to cite this URL:
Kenawy N, Pilz DT, Watts P. Familial unilateral Brown syndrome. Indian J Ophthalmol [serial online] 2008 [cited 2024 Mar 28 ];56:430-434
Available from: https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2008;volume=56;issue=5;spage=430;epage=434;aulast=Kenawy;type=0 |
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