Indian Journal of Ophthalmology

REVIEW ARTICLE
Year
: 2017  |  Volume : 65  |  Issue : 8  |  Page : 673--677

A literature review and update on the incidence and microbiology spectrum of postcataract surgery endophthalmitis over past two decades in India


Prajna Lalitha1, Sabyasachi Sengupta2, Ravilla D Ravindran3, Savitri Sharma4, Joveeta Joseph4, Vikas Ambiya5, Taraprasad Das5 
1 Department of Microbiology Laboratory, Aravind Eye Hospital, Madurai, Tamil Nadu, India
2 Retina Service, Aravind Eye Hospital, Puducherry, India
3 Department of Cataract, Aravind Eye Hospital, Madurai, Tamil Nadu, India
4 Jhaveri Microbiology Laboratory, Hyderabad, Telangana, India
5 Srimati Kanuri Shantamma Retina Vitreous service, L V Prasad Eye Institute, Hyderabad, Telangana, India

Correspondence Address:
Taraprasad Das
Srimati Kanuri Santhamma Retina Vitreous Service, L V Prasad Eye Institute, Road No. 2, Banjara Hills, Hyderabad . 500 034, Telangana
India

Purpose: The purpose of this study was to review the incidence and microbiology of acute postcataract surgery endophthalmitis in India. Methods: Systematic review of English-language PubMed referenced articles on endophthalmitis in India published in the past 21 years (January 1992–December 2012), and retrospective chart review of 2 major eye care facilities in India in the past 5 years (January 2010–December 2014) were done. The incidence data were collected from articles that described “in-house” endophthalmitis and the microbiology data were collected from all articles. Both incidence and microbiological data of endophthalmitis were collected from two large eye care facilities. Case reports were excluded, except for the articles on cluster infection. Results: Six of 99 published articles reported the incidence of “in-house” acute postcataract surgery endophthalmitis, 8 articles reported the microbiology spectrum, and 11 articles described cluster infection. The clinical endophthalmitis incidence was between 0.04% and 0.15%. In two large eye care facilities, the clinical endophthalmitis incidence was 0.08% and 0.16%; the culture proven endophthalmitis was 0.02% and 0.08%. Gram-positive cocci (44%-64.8%; commonly, Staphylococcus species), and Gram-negative bacilli (26.2%–43%; commonly Pseudomonas species) were common bacteria in south India. Fungi (16.7%-70%; commonly Aspergillus flavus) were the common organisms in north India. Pseudomonas aeruginosa (73.3%) was the major organism in cluster infections. Conclusions: The incidence of postcataract surgery clinical endophthalmitis in India is nearly similar to the world literature. There is a regional difference in microbiological spectrum. A registry with regular and uniform national reporting will help formulate region specific management guidelines.


How to cite this article:
Lalitha P, Sengupta S, Ravindran RD, Sharma S, Joseph J, Ambiya V, Das T. A literature review and update on the incidence and microbiology spectrum of postcataract surgery endophthalmitis over past two decades in India.Indian J Ophthalmol 2017;65:673-677


How to cite this URL:
Lalitha P, Sengupta S, Ravindran RD, Sharma S, Joseph J, Ambiya V, Das T. A literature review and update on the incidence and microbiology spectrum of postcataract surgery endophthalmitis over past two decades in India. Indian J Ophthalmol [serial online] 2017 [cited 2020 Dec 5 ];65:673-677
Available from: https://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=8;spage=673;epage=677;aulast=Lalitha;type=0