OPHTHALMIC IMAGE
Year : 2020 | Volume
: 68 | Issue : 10 | Page : 2263-
Swiss cheese retina
Manavi D Sindal, M Arthi Vitreoretina Services, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Pondicherry, India
Correspondence Address:
Dr. Manavi D Sindal Vitreoretina Services, Aravind Eye Hospital, Thavalakuppam, Cuddalore Main Road, Pondicherry - 605 007 India
How to cite this article:
Sindal MD, Arthi M. Swiss cheese retina.Indian J Ophthalmol 2020;68:2263-2263
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How to cite this URL:
Sindal MD, Arthi M. Swiss cheese retina. Indian J Ophthalmol [serial online] 2020 [cited 2024 Mar 28 ];68:2263-2263
Available from: https://journals.lww.com/ijo/pages/default.aspx/text.asp?2020/68/10/2263/295765 |
Full Text
A 12-year-old boy presented with defective vision OU (OD 20/200, OS 20/40). Fundus examination OD revealed foveoschisis with multiple outer retinal holes with retinal detachment (RD) with subretinal gliotic bands [Figure 1]. OS had foveoschisis with vitreous veils. Optical coherence tomography confirmed foveoschisis. Full-field electroretinogram showed reduced b-wave with preserved a wave. Diagnosis of juvenile X-linked retinoschisis (JXLR) with RD was made.{Figure 1}
JXLR is caused due to the mutations in the RS1 gene on Xp22.1 coding for retinoschisin.[1] The split occurs in the nerve fiber layer. Genetic trials with RS1 knockout mice have shown better b-wave function.[2]
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
References
1 | Sikkink SK, Biswas S, Parry NRA, Stanga PE, Trump D. X-linked retinoschisis: An update. J Med Genet 2007;44:225-32. |
2 | Kjellstrom S, Bush RA, Zeng Y, Takada Y, Sieving PA. Retinoschisin gene therapy and natural history in the Rs1h-KO mouse: Long-term rescue from retinal degeneration. Invest Ophthalmol Vis Sci 2007;48:3837-45. |
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