Indian Journal of Ophthalmology

CASE REPORT
Year
: 2020  |  Volume : 68  |  Issue : 10  |  Page : 2270--2272

The painless eye: Neurotrophic keratitis in a child suffering from hereditary sensory autonomic neuropathy type IV


Aditya Sethi1, Srikanth Ramasubramanian2, Meenakshi Swaminathan2 
1 Department of Pediatric Ophthalmology and Strabismus, Arunodaya Deseret Eye Hospital, Gurgaon, Haryana, India
2 Department of Pediatric Ophthalmology and Strabismus, Sankara Nethralaya, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Aditya Sethi
Arunodaya Deseret Eye Hospital, Sector 55, Plot NH4, Gurgaon - 122 011, Haryana
India

Hereditary sensory autonomic neuropathy (HSAN) is a group of inherited disorders (total 5 types) that are associated with sensory dysfunction and varying degrees of autonomic dysfunction. HSAN type IV (HSAN-IV) or congenital insensitivity to pain and anhidrosis (CIPA) is a rare genetic disorder inherited in an autosomal recessive manner. We report a case of this very rare genetic disease in a 3-year-old girl child, born to a family in north India with ocular features of neurotrophic keratitis. The diagnosis was made clinically based on the hallmark features of insensitivity to pain and temperature, anhidrosis, self-mutilating behavior with multiple recurrent oral ulcers, nasal bleeds, multiple trophic ulcers over joints, and decreased intellect.


How to cite this article:
Sethi A, Ramasubramanian S, Swaminathan M. The painless eye: Neurotrophic keratitis in a child suffering from hereditary sensory autonomic neuropathy type IV.Indian J Ophthalmol 2020;68:2270-2272


How to cite this URL:
Sethi A, Ramasubramanian S, Swaminathan M. The painless eye: Neurotrophic keratitis in a child suffering from hereditary sensory autonomic neuropathy type IV. Indian J Ophthalmol [serial online] 2020 [cited 2024 Mar 29 ];68:2270-2272
Available from: https://journals.lww.com/ijo/pages/default.aspx/article.asp?issn=0301-4738;year=2020;volume=68;issue=10;spage=2270;epage=2272;aulast=Sethi;type=0