In the present study on 60 normal subjects, the effect of 0.5% timolol eye drops on intraocular tension was assessed in the presence of oral indomethacin. The subjects were categorized in four groups for comparing the results. Also the side effects of timolol maleate were noted. The following conclusions were made:­ 1. In cases in whom indomethacin was given along with timolol drops, average fall in intraocular tension was almost identical with those in whom timolol alone was used. 2. The ocular hypotensive effect of timolol maleate eve drops is not attenuated by indomethacin given orally; but before we can conclude that the simultaneous administration of timolol maleate eye drops and indomethacin is entirely without risk of attenuation. We must study the effect of combined administration in patients with glaucoma.

Surgical management of glaucoma may include many different procedures, but filtering surgery is the most frequent. The subject of operative failure following glaucoma surgery is extremely important to every ophthalmo­logist who does glaucoma surgery. More over, it is most distressing; that what initially appears to he a clinical success eventually proves to be a failure. If we can analyse the patients operated for glaucoma where satisfactory control is not achieved, we can choose a safer and more successful procedure.

A simple technique of combined gonio punch and intracapsular lens extraction with a fornix based conjunctival flap is described with encouraging results of pressure control (84%). It is ate as effective as trabeculectomy and an easy procedure for patients with cataract and either open or closed angle glaucoma The importance of frequent follow up in the post operative period especially in patients with primary open angle glaucoma emphasised.

Intraocular pressure was measured before, at 2 hours & after haemodialysis in 75 uraemic patients of Indian origin, undergoing haemodialysis. There was no significant rise in intra­ocular pressure in these patients.

A new modified surgical technique is described in five cases of advanced neovascular glaucoma. The procedure included excision of a large trabecular segment, non penetrating cyclodiathermy, destruction of iris new vessels and wide sector iridectomy. The preliminary results are evaluated and are quite encouraging.

Results of repair of cont­racted sockets by mucous membrane grafting obtained from the lip and cheek in 21 eases is presented. Finer points in mucous membrane grafting are highlight led. A snugly fitting conformer with multiple holes is a prerequisite for proper reconstruction of the socket The value of a larger size thin graft with the use of fornix forming sutures and tarsorrhaphy are emphasized.

1704 cases of ocular injuries were seen in 7 years. Of these, 1039 cases had extraocular injuries. Foreign bodies were the commonest - 1298 (90.2%), followed by lid lacerations (7.7%). 250 cases had intraocular injuries and these have been analysed with reference to the clinical presentation. Perforating injuries were seen in 173 eves (69.2%). The most common manifestation was corneal tear (89.3%) 135 (78.03%) cases had uveal prolapse. Among the 77 cases of blunt injuries there was subluxation of the lens in 30 eves (35.96%), hvpheama in 21 eves (27.2%) and secondary glaucoma in 17 eves (22.07%).

The visual outcome in 309 cases of ocular trauma hospitalised over a 7 year period has been studied. There was total visual loss in 63 patients (20.3%) and poor vision in 108 (34.60%), moder­ate visual impairment was seen in 35 (13.92%) and good vision retained in 83 (26.89%). In a small number of patients visual assessment was not possible (3.88%).

Seventy children with cere­bral palsy were examined for aetiological factors responsible, type of disorder and ocular abnormalities. The overall inci­dence of ocular abnormalities was 68.69%, the highest frequency being of squint (35.7%). Other anomalies detected inclu­ded refractive errors (28.5%), optic atrophy (10%) and coloboma (2.9%). Most children were spastic quadriplegics with asphyxia as the major aetiological factor. The study created an awareness amongst parents of these children. The visual status of those affected could be improved for imparting education and training in a better way.

In a dynamic field of Contact Lens Solutions maintenance of high standards of anti-microbial activity is a must Resterilization Activity Time' is a universally accepted yardstick for such an evaluation. In this study eight brands of indigenous popular solutions alongwith two FDA approved solutions were tested for their sterilization efficacy: Standardized suspensions of Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Aspergillus fumigatus were used for the purpose. It was observed that the contact lens solutions available ir, the domestic market were not upto the mark Suggestions for improvement have also been made.

A total of 82 patients suffering from corneal ulcer were treated with framycetin 0.5%, gentamicin 3 mg./ml, chloramphenicol 0.4% and a neomycin combination containing Polymixin B sulphate 5000 u, neomycin sulphate 1700 u and gramicidin 0.025 mg/mL in a Randomised comparative study. The commonest organism isolated was Staphylococcus followed by Pneumococcus, Streptococcus and Pseudomonas. The in vitro sensitivity of these isolates to framycetin was higher than that to others Framycetin produced both earlier and a greater degree of improvement in mean score of signs and symptoms than the other antibiotics. It can thus be concluded that framycetin has a better profile of antibacterial activity and clinical efficacy than some other commonly used topical antibiotics in the treatment of corneal ulcer.

A case of Loiasis in a Nigerian male presenting in an unusual manner with two adult worms, one under­neath the conjunctiva of the left eye and another in subcutaneous tissue below the sternal end of the left clavicle, is reported This was associated with calabar swell­ings, and microfilariae in the peripheral blood smear taken during day time. It was diagnosed by the morphology of the adult worms removed surgically and of the microfilariae.

One case of microphthalmos with upper eye lid cyst in the right eye and malformed left eye is presented. The cyst with microphthalmos was excised which demonstrated a nearly normal anterior segment but disorganized and folded retina and choroid with thin sclera.