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2018| September | Volume 66 | Issue 9
Online since
August 20, 2018
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REVIEW ARTICLE
Lamellar keratoplasty techniques
Nadisha P Singh, Dalia G Said, Harminder Singh Dua
September 2018, 66(9):1239-1250
DOI
:10.4103/ijo.IJO_95_18
PMID
:30127133
Lamellar keratoplasty (LK) has revolutionized corneal graft surgery in several ways. Deep anterior LK (DALK) has eliminated risk of failure due to endothelial rejection. Endothelial keratoplasty (EK) has almost eliminated induced astigmatism and the “weak” graft–host junction as seen with penetrating keratoplasty (PK) and also reduced the risk of endothelial rejection. LK provided new insights into posterior corneal anatomy that led to better understanding and performance of DALK and to the development of another EK procedure, namely pre-Descemet's EK (PDEK). Surgical procedures for LK were further refined based on the improved understanding and are able to deliver better surgical outcomes in terms of structural integrity and long-term patient satisfaction, reducing the need of further surgeries and minimizing patient discomfort. In most specialist centers, anterior lamellar techniques like DALK and EK techniques like Descemet's stripping EK (DSEK) and Descemet's membrane EK (DMEK) have replaced the full-thickness PK where possible. The introduction of microkeratome, femtosecond laser, and PDEK clamp have made LK techniques easier and more predictable and have led to the innovation of another LK procedure, namely Bowman membrane transplant (BMT). In this article, we discuss the evolution of different surgical techniques, their principles, main outcomes, and limitations. To date, experience with BMT is limited, but DALK has become the gold standard for anterior LK. The EK procedures too have undergone a rapid transition from DSEK to DMEK and PDEK emerging as a viable option. Ultrathin-DSEK may still have a role in modern EK.
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EDITORIAL
Sebaceous gland carcinoma: Can we do better?
Santosh G Honavar
September 2018, 66(9):1235-1237
DOI
:10.4103/ijo.IJO_1370_18
PMID
:30127131
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3
OPHTHALMIC IMAGES
Punctate epithelial keratoconjunctivitis: A microsporidial infestation
Rohit Dhakal, Muralidhar Ramappa, Savitri Sharma
September 2018, 66(9):1327-1328
DOI
:10.4103/ijo.IJO_917_17
PMID
:30127158
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2
ORIGINAL ARTICLES
Knowledge and practice patterns of Intensive Care Unit nurses towards eye care in Chhattisgarh state
Sonal Vyas, Ashish Mahobia, Sangeeta Bawankure
September 2018, 66(9):1251-1255
DOI
:10.4103/ijo.IJO_115_18
PMID
:30127134
Purpose:
The aim of the study was to present the level of knowledge and practice patterns regarding exposure keratopathy in mechanically ventilated patients among Intensive Care Unit (ICU) nurses in Chhattisgarh state.
Methods:
A previously validated semi-structured questionnaire was administered in the ICU of six multispecialty hospitals in Chhattisgarh in 2014–2015. Demography included age, gender, level of education, and months of working in ICU. Most of the questions dealt with frequency of eyelid closure assessment, frequency of cleaning of eyes with saline gauze, using a protocol-based approach for eye care, and documentation of ophthalmic complications. Common barriers to delivery of eye care such as shortage of time and too much writing tasks were also inquired.
Results:
Our study included 120 nurses. They worked for mean 22.9 ± 17.8 months in ICU. Knowledge about high risk of exposure keratopathy in ventilated patient was present in 93% (78%; 95% confidence interval [CI]) nurses. Only six nurses (5%) followed a strict protocol for eye care, 52 nurses (43%) checked for eyelid closure in the ventilated patients, and 58 (48%) cleaned the eyes frequently. Those who were aware of exposure keratopathy checked eyelid closure (73% vs. 48%) and cleaned eyes with saline gauze more frequently (24% vs. 4%). Nurses in cardiac ICU were significantly lesser aware of exposure complications compared to medical ICU nurses (40% reduction in awareness, 95% CI = 0.37–0.98,
P
= 0.04).
Conclusion:
Although there is high awareness, practice patterns of ICU nurses were less than desired. Educational initiatives should focus on weaknesses in knowledge and practice noted to improve eye care of patients in ICU.
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Corneal endothelial changes in patients with vitamin D deficiency
Cem Cankaya, Tongabay Cumurcu, Abuzer Gunduz
September 2018, 66(9):1256-1261
DOI
:10.4103/ijo.IJO_238_18
PMID
:30127135
Purpose:
The purpose of this study is to evaluate the effect of vitamin D deficiency on corneal endothelial layer using specular microscopy.
Methods:
Fifty-eight eyes of 58 patients whose vitamin D level was below 15 ng/ml and who had no ocular pathology were included in the study (Group 1). Forty eyes of 40 age-and sex-matched subjects were enrolled as control group (Group 2). Corneal endothelial cell density (CD), coefficient of variation (CV), hexagonal cell ratio (HEX), and central corneal thickness (CCT) were measured using specular microscopy (Konan Medical Inc., Nishinomiya, Japan). The obtained data were compared between the groups.
Results:
There was no significant difference between the groups in terms of age and gender (
P
= 0.344,
P
= 0.399, respectively). The mean CD value was 2772.79 ± 202.21 cells/mm
2
in Group 1 and 2954.97 ± 116.89 cells/mm
2
in Group 2 (
P
= 0.001). The mean CV value was 30.31 ± 3.65 in Group 1 and 28.20 ± 2.71 in Group 2 (
P
= 0.003). The mean HEX value was 46.56 ± 6.32 in Group 1 and 51.07 ± 5.28 in Group 2 (
P
= 0.001). The mean CCT value was 555.87 ± 36.90 μ in group 1 and 549.0 ± 37.39 μ in Group 2 (
P
= 0.96).
Conclusion:
Vitamin D deficiency may affect the corneal endothelial layer. Patients with vitamin D deficiency should be evaluated for endothelial parameters in particular before an intraocular surgery. Further studies are needed to confirm our results.
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Baseline morphological characteristics as predictors of final visual acuity in patients with branch retinal vein occlusions: MARVEL report no. 3
Raja Narayanan, Michael W Stewart, Jay Chhablani, Bhavik Panchal, Rajeev Reddy Pappuru, Taraprasad Das, Subhadra Jalali, M Hasnat Ali
September 2018, 66(9):1291-1294
DOI
:10.4103/ijo.IJO_342_18
PMID
:30127143
Purpose:
To determine the predictive values of baseline optical coherence tomography (OCT) abnormalities on 12-month visual acuity changes in eyes with macular edema (ME) caused by branch retinal vein occlusions (BRVO).
Methods:
We performed a
post hoc
analysis of data from 75 participants in the 12-month MARVEL trial. OCT abnormalities at baseline, including ganglion cell layer cystoid spaces (GCL), intraretinal hyper-reflective dots, and central subfield thickness (CST), were correlated with improvements in visual acuity and the number of anti-vascular endothelial growth factor injections required using a multivariate regression model.
Results:
Eyes with baseline CST > 500 μm had greater visual gains compared to those with CST <500 μm (+21.09 vs +16.08 letters,
P
= 0.04). Eyes with hyper-reflective dots (+13.97 vs +19.93 letters,
P
= 0.02), and GCL cysts (+9.8 vs +18.9,
P
= 0.003) had inferior gains in visual acuity. Neurosensory macular detachments at the baseline did not affect gains in visual acuity. Ninety percent of the gain in visual acuity was recorded after two injections and was maintained until month 12.
Conclusion:
Baseline OCT of <500 μm, hyper-reflective dots, and GCL cystoid spaces are associated with poorer gains in visual acuity. Most of the visual gain occurs after two injections.
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SURGICAL TECHNIQUE
A multipronged approach to prevent Argentinian flag sign in intumescent cataracts
Deepika Dhingra, Monika Balyan, Chintan Malhotra, Vikash Rohilla, Vaneet Jakhar, Arun Kumar Jain
September 2018, 66(9):1304-1306
DOI
:10.4103/ijo.IJO_51_18
PMID
:30127146
In this communication, we describe a technique for creation of a single stage, adequately sized capsulorrhexis in intumescent cataracts by depressurizing the anterior and posterior intralenticular compartments in a nonleaky anterior chamber (AC) to prevent capsulorrhexis extension and Argentina flag sign. Initially, an incomplete main-port incision is made by the partial entry of a 2.2-mm keratome. A cohesive dispersive ophthalmic viscosurgical device (OVD) is injected into AC. Standard side-port incisions are made, followed by anterior capsular staining. The fluid cortex in anterior intralenticular compartment is aspirated by puncturing anterior capsule in the center using a 30-gauge needle entered through a separate limbal stab incision. The nucleus edge is gently tipped posteriorly with the needle tip to release the fluid from posterior intralenticular compartment also and as much fluid aspirated as possible. OVD is again injected and capsulorrhexis is performed in a single stage using micro-capsulorrhexis forceps.
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ORIGINAL ARTICLES
Precision pulse capsulotomy in phacoemulsification: Clinical experience in Indian eyes
Jai A Kelkar, Hetal M Mehta, Aditya S Kelkar, Aanchal A Agarwal, Akshay A Kothari, Shreekant B Kelkar
September 2018, 66(9):1272-1277
DOI
:10.4103/ijo.IJO_146_18
PMID
:30127138
Purpose:
To evaluate the surgical outcome of precision pulse capsulotomy (PPC) in phacoemulsification surgery.
Methods:
One hundred twenty-three eyes of 99 consecutive patients who underwent phacoemulsification with PPC through a 2.8 mm clear corneal incision were prospectively studied at a tertiary care centre. The size, shape of capsulotomy and intraoperative capsulotomy, and surgery-related complications were noted. Visual outcome, IOL stability, and signs of capsular opacification/contraction were evaluated at 3 and 6 months.
Results:
The mean age of patients was 49.5 ± 7.77 years. Complete, circular capsulotomy averaging 5.5 mm diameter was achieved in 117 of 123 eyes. In seven eyes, we experienced complications like capsulorhexis tear (
n
= 6) and inadvertent iris capture (
n
= 1). Probe malfunction occurred in six cases. Stable intracapsular intraocular lens (IOLs) fixation and centration was achieved in all eyes. None of the eyes had any significant posterior capsular opacification or capsular contraction at 3 and 6 months. In one eye anterior capsular opacification at the capsulotomy edge was noted at 6 months.
Conclusion:
PPC is a useful device for achieving a perfectly round capsulorrhexis. However, it has a learning curve and chances of skip areas in capsulorhexis, capsular tag, and its extension should be kept in mind. Special care should be taken in initial cases and while operating on eyes with poorly dilating pupil and mature cataracts.
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The subjectivity of objective evaluation of torsion on fundus photographs by practicing strabismologists
Jitendra Jethani, Paaraj Dave
September 2018, 66(9):1301-1303
DOI
:10.4103/ijo.IJO_182_17
PMID
:30127145
Purpose:
To assess the variability of assessing the ocular torsion on fundus photographs among strabismus surgeons.
Methods:
This was a prospective, noninterventional, clinical trial involving 16 trained and experienced squint surgeons participated in the study. Two videos were prepared of a total of 10 fundus pictures with or without lines for disc foveal angle. The first video had a 4 s viewing time for each fundus image. The second video had the disc foveal lines drawn and a similar 4 s viewing time for each image. The participants were asked to grade the torsion. The primary outcome measure was to assess the agreement between the raters for ocular torsion measurement. Difference in the response of observers from the standard response was the secondary outcome measure.
Results:
A 4 s viewing time was given to mimic the exposure time in the clinic while assessing torsion in a patient. Large variability was found among the responses. The kappa test was done for comparing the agreement between various observers which ranged from slight to fair (<0.40). There was no difference in torsion grading in 30.6% and 26.3% responses in the first and second video from the standard response, respectively. When a limit of ±1 grade was taken as acceptable for the responses, 66.2% for the first and 68.7% for the second video respectively were similar to standard response.
Conclusion:
There is wide variability in assessing ocular torsion by fundus photography. The level of accuracy does increase with marking the line on photographs but still remains unreliable.
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ONE MINUTE OPHTHALMOLOGY
Pretty peachy
Li-Anne Lim, Basil K Williams Jr., Carol L Shields
September 2018, 66(9):1238-1238
DOI
:10.4103/ijo.IJO_948_18
PMID
:30127132
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LETTERS TO THE EDITOR
Smartphone-based high definition anterior segment photography
Amar Pujari, Ritika Mukhija, Anand Brar Singh, Rohan Chawla, Namrata Sharma, Atul Kumar
September 2018, 66(9):1375-1376
DOI
:10.4103/ijo.IJO_544_18
PMID
:30127180
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ORIGINAL ARTICLES
Angle closure glaucoma in rural and urban populations in eastern India—The Hooghly River Glaucoma Study
Chandrima Paul, Subhrangshu Sengupta, Souvik Banerjee, Sumit Choudhury
September 2018, 66(9):1285-1290
DOI
:10.4103/ijo.IJO_344_18
PMID
:30127142
Purpose:
To estimate the prevalence, features, and associations of primary angle closure disease (PACD) in rural and urban populations from West Bengal in eastern India.
Methods:
This was a population-based cross-sectional study with two arms, rural and urban. The rural study area consisted of 28 contiguous villages from 13 gram panchayats in Balagarh Police Station, with rural base hospital at Dhobapara, Balagarh Police Station, in the village Kuliapara of Hooghly district. A tertiary eye hospital in central Kolkata was the urban study center. Individuals residing in the study area aged 40 years and above were included in this study using multistage random cluster sampling. All subjects underwent a detailed ophthalmic examination at our base hospitals including applanation tonometry, ultrasound pachymetry, gonioscopy, and frequency doubling technology perimetry. Data collected were analyzed using SPSS 13. Multiple logistic regressions were used to analyze risk factors for PACD.
Results:
A total of 7,408 and 7,248 subjects aged 40 years or older were enumerated from Hooghly district and Kolkata city, respectively. PACD was detected in 1.9% subjects in rural arm and 1.54% subjects in the urban arm (
P
< 0.001). In rural arm, 0.3% had PACS, 0.56% had PAC, and 1.03% had PACG. In urban arm, 0.22% had PACS, 0.35% had PAC, and 0.97% had PACG.
Conclusion:
The study concludes that higher age, higher CCT, and shorter axial length/presence of hyperopia are important independent predictors of ACD. ACD is more common in eastern India than previous estimates.
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CASE REPORTS
Posterior lenticonus with persistent fetal vasculature
Sudarshan Khokhar, Chirakshi Dhull, Karthikeyan Mahalingam, Pulak Agarwal
September 2018, 66(9):1335-1336
DOI
:10.4103/ijo.IJO_276_18
PMID
:30127164
A 10 year old girl present with both eyes central cataract with posterior lenticonus. Intraoperative, she was noted to have both eyes persistent fetal vasculature (PFV). To the best of our knowledge, association of bilateral posterior lenticonus and PFV has not been reported before. This supports the hypothesis that PFV has a role in pathogenesis of posterior lenticonus.
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ORIGINAL ARTICLES
Comparison between ropivacaine and bupivacaine in deep topical fornix nerve block anesthesia in patients undergoing cataract surgery by phacoemulsification
Anshika Kashyap, Rahul Varshney, Govind Singh Titiyal, Ajay Kumar Sinha
September 2018, 66(9):1268-1271
DOI
:10.4103/ijo.IJO_100_18
PMID
:30127137
Purpose:
In this study, we intend to analyze ropivacaine and bupivacaine in various parameters during phacoemulsification under deep topical fornix nerve block (DTFNB), a known form of nerve block for phacoemulsification.
Methods:
This prospective randomized study was conducted on 100 patients undergoing elective cataract surgery by phacoemulsification under DTFNB. Patients were divided into two equal groups of fifty patients each, Groups B (bupivacaine) and Group R (ropivacaine). Two sponges, approximately 2 mm × 3 mm dimensions, saturated with either 0.5% bupivacaine or 0.75% ropivacaine were placed deep in the conjunctival fornices to perform the deep topical block. Both groups were evaluated for magnitude of pain and discomfort at various stages of phacoemulsification using a simple pain scoring system. The level of surgeon satisfaction, requirement for supplementary anesthesia, and surgical complications were also evaluated. Quantitative variables between the two groups were compared using unpaired
t
-test. Qualitative variables were correlated using Chi-square test.
Results:
Overall demographic parameters of patients were similar in both groups. Similar mean pain scores were found in the ropivacaine and bupivacaine groups, with no statistical significance. Surgical satisfaction and the need for supplemental anesthesia were also statistically insignificant.
Conclusion:
Ropivacaine is a good alternative for deep topical anesthesia as it has a better safety margin and lesser toxic effect than other comparable local anesthetic agents.
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LETTERS TO THE EDITOR
Transzonular drug delivery during cataract surgery: Is dropless cataract surgery really beneficial?
Suresh K Pandey, Vidushi Sharma
September 2018, 66(9):1377-1379
DOI
:10.4103/ijo.IJO_830_18
PMID
:30127182
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2
CASE REPORTS
Multicolor imaging for retinal nerve fiber layer defect in glaucoma
Tamonash Basu, Dhaivat Shah, Debmalaya Das, Kumar Saurabh, Rupak Roy
September 2018, 66(9):1345-1349
DOI
:10.4103/ijo.IJO_30_18
PMID
:30127168
Glaucoma is a progressive optic neuropathy associated with irreversible loss of retinal ganglion cells (RGC). This emblematic localized retinal nerve fiber layer defect (RNFLD) can be the earliest sign to detect the ongoing glaucomatous damage. Slitlamp biomicroscopy [90D & 78D], colour and redfree fundus photography, OCT & HRT are used conventionally for early detection of RNFLD. Multicolour Imaging (MCI) is a new non-invasive retinal imaging modality available in Spectralis platform which simultaneously acquires three reflectance images of the retina using three individual lasers producing a composite image thereby allowing analysis of changes at various levels within the retina. MCI provides sharper image, enables imaging through small pupil and hazy media. Current report describes 2 cases where in MCI proved superior to CFP and conventional redfree photograph in delineating area of RNFLD. This is the first report of MCI in RNFL imaging. The present report highlights the role of MCI in detection of RNFLD.
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Topiramate-induced acute angle closure with severe panuveitis: A challenging case report
Padmamalini Mahendradas, Snehanka Parab, Rajesh Sasikumar, Ankush Kawali, Bhujang K Shetty
September 2018, 66(9):1342-1344
DOI
:10.4103/ijo.IJO_1192_17
PMID
:30127167
A 36-year-old female presented with the complaints of pain, photophobia, redness, and sudden diminution of vision in both the eyes following topiramate for migraine treatment. On examination, there was panuveitis with angle-closure glaucoma in both the eyes with fibrinous exudate with pigments in the anterior chamber of the left eye. B scan revealed increased choroidal thickness in both the eyes. Serial anterior segment optical coherence tomography scans were done in the left eye to demonstrate the gradual resolution of the fibrin material from the anterior chamber. There was complete resolution of inflammation in both eyes following discontinuation of topiramate and treatment with systemic and topical steroids. There was an improvement in visual acuity in the left eye following complicated cataract surgery.
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Magnetic ocular prosthesis for shallow contracted socket
Ramesh Murthy, Madhulata Umesh
September 2018, 66(9):1372-1373
DOI
:10.4103/ijo.IJO_421_18
PMID
:30127178
Contracted sockets with poor retention of ocular prosthesis are difficult to manage especially when it is a dry socket. A 50-year-old lady with history of irradiation to the socket following enucleation for retinoblastoma reported to us with severe socket contracture, dry socket, and inadequate lid closure with a poorly retained ocular prosthesis. She was using a stone in the socket for support with a cracked stock ocular prosthesis placed over it. A two-piece ocular prosthesis was created with a base and shell with neodymium-boron-ferrous magnets in each part, with good retention and positioning, and this was cosmetically acceptable to the patient. To the best of our knowledge, this is the first report of such a two-piece magnetic ocular prosthesis.
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Multimodal imaging signatures in a case of acute zonal occult outer retinopathy
Dhaivat Shah, Deepika Khedia, Kumar Saurabh, Rupak Roy
September 2018, 66(9):1349-1352
DOI
:10.4103/ijo.IJO_264_18
PMID
:30127169
Acute zonal occult outer retinopathy (AZOOR) is a retinal disease characterized by a slow onset loss of retinal function with minimally evident fundus changes. Patients with AZOOR present with initially progressive scotoma and photopsia. Its pathogenesis has not been definitively determined as of yet. Characteristically, the extent of the visual field defect is unexplained by fundus examination, but there is marked retinal dysfunction, which is evident on multimodal imaging and electrophysiological testing. We herein describe multimodal imaging signatures of AZOOR, in a patient of Indian origin, highlighting the hitherto unreported multicolor channels and near-infrared autofluorescence.
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Successful management of peripapillary choroidal neovascular membrane secondary to idiopathic intracranial hypertension with intravitreal ranibizumab
Nitin Kumar, Basavraj Tigari, Mohit Dogra, Ramandeep Singh
September 2018, 66(9):1358-1360
DOI
:10.4103/ijo.IJO_419_18
PMID
:30127172
Idiopathic intracranial hypertension (IIH) is a common cause of papilledema in young females and causes headache with transient visual loss. Severe visual loss occurs due to optic atrophy or peripapillary choroidal neovascular membrane (PCNVM). PCNVM in IIH has an incidence of 0.5% with a benign course in the majority of patients. Intravitreal Anti-vascular endothelial growth factor agents have anecdotally been used to manage these patients, with complete resolution reported in all cases after a single injection. Our case of IIH-associated PCNVM was treated with three injections of intravitreal ranibizumab with no recurrence at 6-month follow-up.
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1
ORIGINAL ARTICLES
Comparison of posterior lamellar resection versus lumpectomy for initial management of localized tarsal conjunctival sebaceous carcinoma in 54 cases
Sara E Lally, Raksha Rao, Jerry A Shields, Carol L Shields
September 2018, 66(9):1295-1300
DOI
:10.4103/ijo.IJO_239_18
PMID
:30127144
Purpose:
Comparison of outcomes of localized eyelid sebaceous carcinoma (American Joint Committee on Cancer (AJCC) 8
th
edition categories T1, T2, T3) following initial management with posterior lamellar resection (PLR) versus (vs) lumpectomy (nonposterior lamellar resection, non-PLR).
Methods:
This was a retrospective, comparative, interventional case series. Of 54 patients, 26 were managed by PLR and 28 by nonPLR. The main outcome measures were vision loss, orbital exenteration, lymph node metastasis, and remote metastasis were the main outcome measures.
Results:
A comparison of PLR vs nonPLR revealed no difference in mean age at presentation (70 vs 72 years), race (Caucasian 100% vs nonCaucasian 93%), gender (female 54% vs male 71%), entering mean visual acuity (20/30 vs 20/50), or corneal involvement (23% vs 11%). There was significant difference in clinical features with PLR demonstrating greater mean basal diameter (21 mm vs 12 mm,
P
= 0.004), and positive margins were seen more frequently in PLR (69% vs 46%). There was significantly less number of surgical procedures in PLR to achieve complete tumor control (1.7 vs 2.5,
P
= 0.001). Outcomes at mean 55 months follow-up revealed significantly better control with PLR (vs nonPLR) with fewer orbital exenterations (15% vs 43%,
P
= 0.038), fewer lymph node, and systemic metastases (0% vs 39%,
P
< 0.001). There was no significant difference in final mean visual acuity (20/60 vs 20/200).
Conclusion:
For eyelid sebaceous carcinoma, the initial management is critical to the patient's outcome. PLR demonstrates superior outcomes with regard to preservation of visual acuity and avoidance of exenterations, lymph node metastases, and systemic metastases compared to patients managed with other techniques.
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SURGICAL TECHNIQUE
Swivel haptics anterior capsule-fixated intraocular lens
Sri Ganesh, Sheetal Brar
September 2018, 66(9):1307-1309
DOI
:10.4103/ijo.IJO_665_17
PMID
:30127147
The purpose of the study is to report the feasibility of implantation of a new design of anterior capsule-fixated intraocular lens (IOL). The new IOL design is a foldable, hydrophilic, open-loop posterior chamber IOL with two extra polymethyl methacrylate swivel haptics created on the optic surface to capture the anterior capsulotomy after the IOL is implanted in the bag. In the pilot phase, the new IOL was implanted in 10 eyes of 10 patients of which 8 eyes underwent phacoemulsification and 2 eyes had laser cataract surgery. The mean spherical equivalent changed from *1.75 D to −0.75 D at 6 months. Postoperatively, from 1 week to 6 months, all eyes showed stable refraction and anterior chamber depth with no evidence of decentration. Subjective questionnaire revealed high patient satisfaction with no complaints of dysphotopsia. No intra- or postoperative complications such as swivel haptic breakage, iris chafing, pigment dispersion, postoperative uveitis, or endophthalmitis occurred in any of the eyes necessitating explantation of the IOL. The new IOL design was feasible to implant and provided satisfactory outcomes in terms of no dysphotopsias and stable effective lens position.
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3
CASE REPORTS
In-the-bag multifocal intraocular lens causing pigment dispersion and refractory secondary ocular hypertension
Sirisha Senthil, Isha G Grover
September 2018, 66(9):1339-1341
DOI
:10.4103/ijo.IJO_198_18
PMID
:30127166
Pigment dispersion and elevated intraocular pressure (IOP) with sulcus placed hydrophobic acrylic intraocular lenses (IOLs) are described and are rare with in-the-bag IOLs. We report a case of a young lady with elevated IOP and pigment dispersion in one eye following an uneventful phacoemulsification and multifocal IOL implantation. The eye had eccentric capsulorrhexis and localized capsular fibrosis with anterior displacement of the IOL optic, resulting in pigment dispersion. The uncontrolled IOP and continued pigment dispersion were managed with IOL exchange (three-piece IOL) followed by filtration surgery, which helped to resolve the condition successfully.
[ABSTRACT]
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1,949
213
2
OPHTHALMIC IMAGES
Traumatic expulsion of intact iris in toto
Seema Ramkrishnan, Prabu Baskaran, Arti Jain
September 2018, 66(9):1329-1330
DOI
:10.4103/ijo.IJO_2_18
PMID
:30127160
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,922
154
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PHOTO ESSAY
Multimodal imaging in Multifocal Best disease
Dhaivat Shah, Kumar Saurabh, Rupak Roy
September 2018, 66(9):1313-1315
DOI
:10.4103/ijo.IJO_70_18
PMID
:30127150
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[CITATIONS]
[PubMed]
1,803
234
2
Corneal regularization following customized corneal collagen cross-linking
Gitansha Shreyas Sachdev, Shreyas Ramamurthy
September 2018, 66(9):1310-1311
DOI
:10.4103/ijo.IJO_1101_17
PMID
:30127148
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[CITATIONS]
[PubMed]
1,773
253
3
ORIGINAL ARTICLE
Combined cataract extraction with a new nonvalved glaucoma drainage device in adult eyes with cataract and refractory glaucoma
Divya P Rao, Vanita Pathak-Ray
September 2018, 66(9):1278-1283
DOI
:10.4103/ijo.IJO_195_18
PMID
:30127140
Purpose:
The purpose of the study is to report the outcomes of simultaneous cataract extraction (CE) and a new nonvalved glaucoma drainage device (GDD), Aurolab Aqueous Drainage Implant (AADI), in eyes with cataract and refractory glaucoma.
Methods:
This was a non-comparative, interventional, retrospective study. Consecutive patients who underwent AADI together with phacoemulsification from June-2015 to January-2017 by a single fellowship trained glaucoma surgeon with documented 3-months of follow-up were included. The main outcomes were intraocular pressure (IOP), antiglaucoma medication (AGM), visual acuity, and complications.
Results:
We included 19 eyes of 17 patients with average follow-up of 14.4 ± 8.4 months. IOP and AGM reduced from 36.9 ± 11.1 mmHg and 4 ± 0.8 preoperatively to 12 ± 4.5 mmHg and 0.8 ± 1.2, respectively (
P
< 0.001). Complications were seen in seven eyes (36.8%). Total success was seen in 17 eyes (89.5%). None of the patients lost vision.
Conclusion:
Combining cataract extraction with the new non-valved Aurolab Aqueous Drainage Implant, appears to be an effective and safe technique in eyes with refractory glaucoma and cataract. Larger studies and further follow-up is recommended for such patients.
[ABSTRACT]
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1,681
285
6
OPHTHALMIC IMAGES
Pseudohypopyon—a red flag sign of malignancy
Jitender Jinagal, Parul C Gupta, Deepak Bansal, Arvind Rajwanshi, Jagat Ram
September 2018, 66(9):1328-1329
DOI
:10.4103/ijo.IJO_378_18
PMID
:30127159
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[CITATIONS]
[PubMed]
1,749
215
2
ORIGINAL ARTICLES
Repeatability of ARK-30 in a pediatric population
Laura Hernandez-Moreno, Ana Vallelado-Alvarez, Raul Martin
September 2018, 66(9):1262-1267
DOI
:10.4103/ijo.IJO_266_18
PMID
:30127136
Purpose:
To determine repeatability and agreement of the ARK-30 handheld autorefractor with retinoscopy under cycloplegic and noncycloplegic conditions in children.
Methods:
Three consecutive autorefractor measurements (with and without cycloplegia) and retinoscopy were performed and compared in 30 randomized eyes of 30 children (mean age of 6.7 ± 2.7 years with spherical equivalent [SE] refraction from ‒4.01 to +7.38 D) in a cross-section and masked study. Bland–Altman analysis of autorefractor measurements (with and without cycloplegia) and agreement with retinoscopy were calculated with conventional notation (sphere [Sph] and cylinder [Cyl]) and vector notation (SE, J
0
, and J
45
coefficients).
Results:
ARK-30 measurements without cycloplegia were lower than under cycloplegic conditions (Sph: ‒0.52 ± 2.37 D vs + 0.86 ± 2.60 D,
P
< 0.01; Cyl: ‒0.83 ± 0.80 D versus ‒0.78 ± 0.77 D,
P
= 0.37; and SE: ‒0.94 ± 2.19 D vs + 0.47 ± 2.44 D,
P
< 0.01, respectively) and statistically different (
P
< 0.03) from retinoscopy (Shp: +0.83 ± 2.66 D; Cyl: ‒0.71 ± 0.87 D; SE: +0.51 ± 2.49 D). Without statistical differences were in J
0
and J
45
coefficients. Cyloplegic autorefraction measures were not found to be statistically significantly different to retinoscopy measures. ARK-30 under cycloplegia shows better repeatability with lower limits of agreement (LoA) in Sph (LoA: ‒0.66 to +0.69 D), and SE (LoA: ‒0.66 to +0.65 D) than without cycloplegia (LoA: ‒1.45 to +1.77 D, and ‒1.38 to +1.74 D, respectively).
Conclusion:
Under noncycloplegic conditions, ARK-30 autorefractor has low repeatability and a tendency toward minus over correction in children. However, repeatability and agreement with retinoscopy under cycloplegic conditions allow use of ARK-30 in children to estimate refraction but not to substitute gold standard retinoscopic refraction.
[ABSTRACT]
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1,740
204
4
PHOTO ESSAY
Central retinal vein occlusion revealing celiac disease: The first report of two cases from India
Ravinder Kaur Malhi, Abhinav Dhami, Nirmaljeet Singh Malhi, Amit Soni, Gobinder Singh Dhami
September 2018, 66(9):1315-1317
DOI
:10.4103/ijo.IJO_351_18
PMID
:30127151
[ABSTRACT]
[FULL TEXT]
[PDF]
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[CITATIONS]
[PubMed]
1,675
210
6
It is an Alport syndrome, not a simple hypertensive retinopathy
Aruna Kumari Gadde, Arjun Srirampur, Sunny Manwani, Satish Agraharam
September 2018, 66(9):1319-1321
DOI
:10.4103/ijo.IJO_426_18
PMID
:30127153
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,668
210
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LETTERS TO THE EDITOR
Amblyopia: It is time to take action
Piyush Kohli, RK Bansal, Tanvi Soni, Anugya Agrawal
September 2018, 66(9):1374-1375
DOI
:10.4103/ijo.IJO_89_18
PMID
:30127179
[FULL TEXT]
[PDF]
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[CITATIONS]
[PubMed]
1,623
224
1
CASE REPORTS
Recurrent isolated oculomotor nerve palsy caused by schwannoma in a pediatric patient
Donghun Lee, Won Jae Kim, Myung Mi Kim
September 2018, 66(9):1367-1369
DOI
:10.4103/ijo.IJO_340_18
PMID
:30127176
Isolated schwannomas of motor nerves to extraocular muscles are uncommon. In addition, most previous studies on oculomotor nerve schwannoma discuss adult patients, and pediatric cases are rare. We report a 10-year-old girl who developed recurrent oculomotor nerve palsy caused by schwannoma without any vascular malformation. Although the incidence is rare in pediatric patient, the recurrent isolated oculomotor nerve palsy due to schwannoma can develop, and it should be considered in the differential diagnosis of ocular motility disorders in pediatric patients. Careful imaging evaluation is needed to identify schwannoma due to its small size, deep location in the brain, and rarity.
[ABSTRACT]
[FULL TEXT]
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1,604
199
3
Management of cataract in Werner syndrome
Rakhi Kusumesh, Bibhuti Prassan Sinha, Anita Ambastha, Santosh Kumar Thakur
September 2018, 66(9):1337-1339
DOI
:10.4103/ijo.IJO_1308_17
PMID
:30127165
Werner syndrome (WS) is a rare progressive disorder. It is characterized by the appearance of unusually accelerated aging (progeria) including bilateral senile cataract. Here, we report a successful management of hypermature cataract in WS.
[ABSTRACT]
[FULL TEXT]
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[PubMed]
1,648
153
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Secondary Coats' response to retinal vasculitis managed with bevacizumab
Priyanka Chaudhary, Abhishek Varshney, Chetan Videkar
September 2018, 66(9):1355-1357
DOI
:10.4103/ijo.IJO_279_18
PMID
:30127171
We report a case of 22-year-old young male who presented with a 3-month history of gradual and painless decrease of vision in his right eye (RE). On ophthalmological examination, best-corrected visual acuity in his RE was counting finger close to the face. Left eye ophthalmic examination was unremarkable. RE indirect ophthalmoscopy revealed multiple telangiectatic vessels, aneurysmal dilations, extensive yellow (lipid) exudation over the posterior pole along with perivascular exudation, and multiple sclerosed vessels in peripheral retina. Fluorescein angiography also revealed progressive leakage from telangiectasias, multiple aneurysmal outpouchings, extensive capillary dropouts, and vascular communicating channels in all quadrants. Spectral-domain-optical coherence tomography of macula demonstrated marked intraretinal fluid. Based on the above findings, a diagnosis of healed retinal vasculitis with Coats'-like response was made. The patient received 4-weekly two intravitreal bevacizumab injections which resulted in stabilization of the retinal findings and improvement in visual acuity.
[ABSTRACT]
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1,535
194
3
First report of palpebral conjunctival inflammatory nodule associated with Demodex species
Ying Li, Ga Eon Kim, Kyung Chul Yoon, Won Choi
September 2018, 66(9):1365-1367
DOI
:10.4103/ijo.IJO_375_18
PMID
:30127175
Demodex
mite infestation of the palpebral conjunctiva as focal inflammatory nodule has been not reported. A 46-year-old man presented with lower palpebral conjunctival nodules in his left eye. Slit-lamp examination showed focal inflammatory nodules at the inferior palpebral conjunctiva accompanied by conjunctival hyperemia and purulent secretion. Excisional biopsy of this lesion was performed. Pathological evaluations revealed inflammatory granuloma associated with
Demodex
species in the palpebral conjunctiva. This is the first report of
Demodex
-related palpebral conjunctival inflammatory nodule and may be helpful in future
Demodex
-associated studies.
[ABSTRACT]
[FULL TEXT]
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[CITATIONS]
[PubMed]
1,546
161
2
Bilateral hemorrhagic proptosis due to an uncommon cause in ocular emergency
Amar Pujari, Ritika Mukhija, Adarsh Shashni, Hameed Obedulla, Rachna Meel, Mandeep S Bajaj
September 2018, 66(9):1370-1371
DOI
:10.4103/ijo.IJO_399_18
PMID
:30127177
A 19-year-old male patient presented to the ocular emergency services with sudden onset of proptosis, pain, and bloody discharge. Further evaluation revealed bilateral visual acuity of finger counting close to face vision with an accurate projection of rays. Computed tomography scan of the head and orbit revealed diffuse orbital hemorrhage (mainly along the ocular coats) in the absence of any subperiosteal or intracranial hemorrhage. A complete hematological workup was done and it revealed decreased factor IX levels (9% of normal) consistent with hemophilia B (Christmas disease). The patient was managed medically with factor IX supplementation. At the end of 6 weeks, patient's visual acuity improved to 20/20 in both the eyes.
[ABSTRACT]
[FULL TEXT]
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1,526
157
2
PHOTO ESSAY
Purtscher-like retinopathy as presenting manifestation of systemic lupus erythromatosus following high-grade fever with myalgia and arthralgia
Amit H Palkar, M Delwar Hossain, Parthopratim Dutta Majumder
September 2018, 66(9):1317-1319
DOI
:10.4103/ijo.IJO_549_18
PMID
:30127152
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[CITATIONS]
[PubMed]
1,473
210
2
CASE REPORTS
Macular cytomegalovirus retinitis following dexamethasone intravitreal implant combined with phacoemulsification
Mohit Dogra, Vikash Rohilla, Mangat Dogra, Ramandeep Singh
September 2018, 66(9):1361-1363
DOI
:10.4103/ijo.IJO_171_18
PMID
:30127173
A 60-year-old diabetic patient, who had undergone a renal transplant 2 years earlier, presented with sudden decrease in vision in his left eye (LE). He had undergone phacoemulsification combined with intravitreal dexamethasone implant injection in his LE 2 months earlier, for coexistent cataract and diabetic macular edema. Examination revealed necrotizing retinitis with hemorrhages in the macula. A diagnosis of cytomegalovirus retinitis was made, which was confirmed on vitreous polymerase chain reaction. Intravitreal and systemic ganciclovir led to the resolution of retinitis and improvement of visual acuity over a follow-up of 9 months.
[ABSTRACT]
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1,442
185
8
OPHTHALMIC IMAGES
Anterior lenticonus associated with Alport syndrome
Jitender Jinagal, Gaurav Gupta, Faisal Thattaruthody, Ritambhra Nada, Jagat Ram
September 2018, 66(9):1330-1331
DOI
:10.4103/ijo.IJO_400_18
PMID
:30127161
[FULL TEXT]
[PDF]
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[EPub]
[CITATIONS]
[PubMed]
1,400
202
1
PHOTO ESSAY
Another brick in the wall
Bipasha Mukherjee, Shebin Salim
September 2018, 66(9):1325-1326
DOI
:10.4103/ijo.IJO_241_18
PMID
:30127157
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,408
170
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OPHTHALMIC IMAGES
Retinal necklace: Chain of cysts in retinal detachment
Shreyas Temkar, Rahul Kumar Bafna, Sourav Damodaran, Divya Agarwal, Vinod Kumar
September 2018, 66(9):1331-1332
DOI
:10.4103/ijo.IJO_56_18
PMID
:30127162
[FULL TEXT]
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[PubMed]
1,397
179
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LETTERS TO THE EDITOR
Burnout in ophthalmologists
Ajay I Dudani
September 2018, 66(9):1376-1377
DOI
:10.4103/ijo.IJO_979_18
PMID
:30127181
[FULL TEXT]
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1,372
200
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COMMENTARY
Commentary: Precision pulse capsulotomy: New technology for capsulorhexis
Lakshey Dudeja
September 2018, 66(9):1276-1277
DOI
:10.4103/ijo.IJO_890_18
PMID
:30127139
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,317
199
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PHOTO ESSAY
Different responses to two consecutive Nd:YAG laser membranotomies at different locations in a 3-week-old sub-internal limiting membrane hemorrhage
Baek-Lok Oh, Hyeong Gon Yu
September 2018, 66(9):1321-1322
DOI
:10.4103/ijo.IJO_310_18
PMID
:30127154
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,351
142
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CASE REPORTS
Optical coherence tomography angiography of fleeting macroaneurysm in retinal racemose angioma
P Mahesh Shanmugam, Sriram Simakurthy, Vinaya Kumar Konana, Rajesh Ramanjulu, K C Divyansh Mishra
September 2018, 66(9):1352-1354
DOI
:10.4103/ijo.IJO_267_18
PMID
:30127170
We present a rare case of retinal racemose angioma complicated with fleeting macroaneurysm (MA). A 50-year-old female presented with diminution of vision in her right eye for 6 years. Fundus examination showed a racemose angioma with hemorrhagic MA temporal to the fovea in the right eye. On subsequent follow-ups, spontaneous thrombosis of MA was noted with the development of new MA inferior to the fovea, with intraretinal hemorrhage extending into the fovea. Focal laser to MA resulted in resolution of MA with improvement in vision. We report optical coherence tomography angiographic features of the fleeting MA in a case of racemose angioma.
[ABSTRACT]
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1,321
167
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PHOTO ESSAY
Microscope-integrated optical coherence tomography-aided intraoperative diagnosis and management of peripheral tractional retinoschisis
Dheepak Sundar, Atul Kumar, Rohan Chawla, Sagnik Sen, Raghav Ravani, Prateek Kakkar, Kartikeya Chatra
September 2018, 66(9):1323-1324
DOI
:10.4103/ijo.IJO_331_18
PMID
:30127155
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[CITATIONS]
[PubMed]
1,266
160
2
LETTERS TO THE EDITOR
Response to: Transzonular drug delivery during cataract surgery: Is dropless cataract surgery really beneficial?
Prafulla K Maharana, Jay K Chhablani, Taraprasad Das, Atul Kumar, Namrata Sharma
September 2018, 66(9):1380-1380
DOI
:10.4103/ijo.IJO_1040_18
PMID
:30127183
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,221
168
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PHOTO ESSAY
In vivo
confocal microscopy of iris in recessive cornea plana with anterior synechiae
Enrico Bruni, Emilio Pedrotti, Paolo Plinio Di Sarro, Mattia Passilongo, Giorgio Marchini
September 2018, 66(9):1311-1313
DOI
:10.4103/ijo.IJO_346_18
PMID
:30127149
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,251
129
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CASE REPORTS
Non-Descemet stripping automated endothelial keratoplasty for post radial keratotomy corneal edema
Sushmita Gaurav Shah, Gaurav Y Shah
September 2018, 66(9):1333-1335
DOI
:10.4103/ijo.IJO_1281_17
PMID
:30127163
An elderly male with monocular status presented with complaints of gradual loss of vision in his left eye. Slit-lamp evaluation revealed postradial keratotomy (RK) corneal decompensation. He underwent non-Descemet stripping automated endothelial keratoplasty (nDSAEK) in his left eye. Postoperatively, his visual acuity improved from counting finger at 1 m to 20/200, J5. Graft adherence was good. A preexisting epiretinal membrane with macular edema was noted, but our patient refused any further surgical intervention for the same. In conclusion, nDSAEK may be considered as an effective treatment modality for the management of post-RK corneal decompensation.
[ABSTRACT]
[FULL TEXT]
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[CITATIONS]
[PubMed]
1,225
153
2
PHOTO ESSAY
In vivo
observation of intracanalicular changes in association with blinking
Swati Singh, Vikas Mittal, Akshay G Nair, Saurabh Kamal
September 2018, 66(9):1324-1325
DOI
:10.4103/ijo.IJO_240_18
PMID
:30127156
[ABSTRACT]
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[CITATIONS]
[PubMed]
1,212
138
1
CASE REPORTS
Commentary: Iatrogenic cytomegaloviral retinitis following intravitreal steroid implantation
S Bala Murugan
September 2018, 66(9):1363-1364
DOI
:10.4103/ijo.IJO_446_18
PMID
:30127174
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,159
141
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COMMENTARY
Commentary: Combined cataract extraction with a new nonvalved glaucoma drainage device in adult eyes with cataract and refractory glaucoma
Harsh Kumar
September 2018, 66(9):1284-1284
DOI
:10.4103/ijo.IJO_1347_18
PMID
:30127141
[FULL TEXT]
[PDF]
[Mobile Full text]
[EPub]
[PubMed]
1,050
151
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