Verapamil eye drops (0.125%) were prepared in phosphate buffer (pH7). Ten patients with unilateral (5 cases) or bilateral (5 cases) ocular hypertension received the drug topically three times daily for two weeks. A significant reduction in the mean ocular tension was observed in 6 right eyes at the end of the first (4.5 mm Hg Schiotz) and second week (7 mm Hg Schiotz) and in 9 left eyes at the end of the second week (6.7 mm Hg Schiotz). The reduction in tension was minimal (1 mm Hg Schiotz) in the eyes with normal initial values. The systolic and diastolic blood pressured dropped by 12.8 mm Hg and 4.0 mm Hg in the first week and by 11.2 mm Hg and 5.4 mm Hg in the second week respectively. There was also a reduction in the mean pulse rate by 7 beats and 13 beats in the first and second week of therapy. These observations indicate persistent hypotensive effect of topical Verapamil on ocular hypertension and some amount of systemic absorption of the drug from eye.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

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School children form an important large target group which must be screened adequately for early detection of eye diseases and prevention of blindness. A total approach in a school eye health programme must include teacher orientation and health education of children in addition to screening for eye diseases. The ocular morbidity pattern in 5135 school children of Jodhpur is discussed in this paper and it is hoped that it will be an indicator to all eye care agencies to help plan their priorities in the delivery of school based eye care.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

In this study, 3,490 children were examined to know the pattern of ocular problems in children in this part of the country. It showed that heritable diseases were quite prevalent, i.e., 41.49%. In this group refractive error, nasolacrimal duct block, and primary squint were most common, while in the non-heritable group various types of conjunctivitis, trauma, foreign bodies, blepharitis and nutritional diseases were most prevalent.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

Tear film flow and stability studies were carried out in healthy population by Schirmer's test-1 and tear film break-up-time (BUT) measurements, respectively. The mean BUT observed was 13.87 +/- 4.79 seconds; however, in 22 percent of cases the values of BUT were even less than the lowest values laid down by various workers, from the Western countries. Maximum dry spots were located in the temporal quadrant.

[ABSTRACT]  [FULL TEXT]    [CITATIONS]  [PubMed]

The results phaco-emulsification aspiration procedure have been evaluated in 50 cataract patients, by observing the final visual acuity achieved and astigmatic error induced, along with incidence of various operative and post-operative complications. Majority of the patients who did not have serious preoperative complications achieved good vision. The procedure has proved to be equally effective for cataracts occurring in the younger age group.

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Acrodermatitis enteropathica is a rare disease affecting infant girls. The skin in these cases develop rashes which start as vesicles and then dries to form erythematous squamous psoriasiform type of lesions. Dystrophy of nails and alopecia with loss of eye lashes and eye brows is also seen. Low serum zinc level is found in these patients and is thought to be the cause of this disease.

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A case of atypical Wilson disease is being reported. Possible mechanism of the process, diagnostic features and CT appearance of brain is described. Early detection and therapy with copper chelating agents result in neurologic and performance improvement of patients.

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Complete dislocation of the lens is a rare feature of Marfan's Syndrome. We observed four cases of bilateral complete posterior dislocation of the lens in established cases of Marfan's Syndrome over a one year period. An ophthalmologist may encounter infrequently, unilateral posterior dislocation in one eye and ectopia lentis in the other, but bilateral spontaneous posterior dislocation is rare. All our cases had associated vitreous degeneration with vitreous herniating into the anterior chamber. The pathogenesis of complete posterior dislocation in Marfan's Syndrome is discussed.

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A rare case of cyst of an ectopic lacrimal gland in the bulbar conjunctiva is reported in a 40 year-old-man. The clinical presentation histopathology, differential diagnosis and treatment of this choristomatous lacrimal ductal cyst (Group IV according to Bullock's classification) is described.

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Atypical lymphoid hyperplasia, a rare variety of orbital tumour occurring in a 60 year old male patient is presented with review of literature with special relation to its diagnostic and prognostic difficulties.

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A rare case of Warthin's tumour, arising from the lid, is being presented. It is probably the first of its kind reported In literature.

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Primary intraorbital meningioma and Schwannoma are rare tumours. For them to occur concurrently, or one following soon after another should be considered a curiosity. We present a 40 year old male who reported with proptosis of the right eye and a meningioma was removed surgically. Within 3 months symptoms recurred and a schwannoma was removed at surgery from the same site. Interesting features of the lesion are presented and discussed.

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Atenolol is a newer betablocker, widely used as an antihypertensive drug. It cause a large and rapid fall in IOP when used orally and topically. A total of 33 patients both having normal and raised IOP were included in the study. The drug was given in a dose of 50 mg. tab. orally once a day for 7 days at 8 A.M. and IOP recorded after 24 hours, 72 hours and on 7th day. It produces significant and sustained fall in IOP in both normal and raised IOP patients besides lowering of systematic B.P. and pulse rate. The IOP on patients with systemic hypertension with Atenolol will be reduced and stoppage of therapy may cause glaucoma damage.

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A prospective study was carried out on 27 patients with optic neuritis. Besides detailed clinical examination, visual evoked responses (VER) were studied utilising the checker board pattern reversal and flash stimuli. The recording with the 30 minute check size was found to be the most consistent both for the controls and the patients. Flash evoked VER was most useful in determining the wave form in cases with severe disruption of the visual pathways. Neither the implicit time nor the amplitude of the VER could be directly correlated to the visual acuity changes or other clinical parameters. Implicit time offered a more reliable criterion for evaluation as compared to the amplitude in patients with optic neuritis. The VER recording helps in serial follow-up of a patient and can indicate previous attacks suffered by the patient.

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A retrospective study on 80 children with uniocular proptosis has been done. Of these 57 had orbital lesions, 19 had periorbital lesions and 4 had intracranial lesions. The clinical, radiological and pathological aspects as well as the management of these conditions are discussed.

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