• Users Online: 2823
  • Home
  • Print this page
  • Email this page
Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
  Access statistics : Table of Contents
   2011| May-June  | Volume 59 | Issue 3  
    Online since May 13, 2011

 
 
  Archives   Previous Issue   Next Issue   Most popular articles   Most cited articles
 
Hide all abstracts  Show selected abstracts  Export selected to
  Viewed PDF Cited
ORIGINAL ARTICLES
Comparative role of intravitreal ranibizumab versus bevacizumab in choroidal neovascular membrane in age-related macular degeneration
Partha Biswas, Subhrangshu Sengupta, Ruby Choudhary, Subhankar Home, Ajoy Paul, Sourav Sinha
May-June 2011, 59(3):191-196
DOI:10.4103/0301-4738.81023  PMID:21586838
Context: Ranibizumab and bevacizumab are used widely for treating patients with choroidal neovascular membrane (CNVM) secondary to age-related macular degeneration (AMD). Aims: To determine and compare the efficacy and safety of intravitreal ranibizumab and bevacizumab in treatment of CNVM due to AMD. Settings and Design: Prospective comparative case series carried out in an eye institute and eye department of a hospital in Kolkata, India. Materials and Methods: One hundred and four eyes with CNVM due to AMD were randomized into two groups. Group A (n=54; 24 occult) received monthly intravitreal ranibizumab injections (0.5 mg in 0.05 ml) and Group B (n=50; 22 occult) received monthly bevacizumab injections (1.25 mg in 0.05 ml) for 3 consecutive months and then as per study criteria. Data analysis done using SPSS software. P-value of <0.05 was considered statistically significant. Results: The mean best corrected visual acuity (BCVA) in the ranibizumab group increased from 58.19 Early Treatment Diabetic Retinopathy Study (ETDRS) letters at baseline to 64 ETDRS letters at month 3 (P<0.001). In bevacizumab group mean BCVA increased from 56.80 to 61.72 ETDRS letters at month 3 (P<0.001). At the end of 18 months, there was no statistically significant difference between groups A and B with respect to change in BCVA (P=0.563) or central macular thickness (CMT; P=0.281), as measured by optical coherence tomography (Stratus OCT 3000). No significant sight-threatening complications developed. Conclusions: Ranibizumab and bevacizumab are equally safe and efficacious in treating CNVM due to AMD.
  6,118 586 18
BRIEF COMMUNICATIONS
Tectonic corneal graft for conjunctival rhinosporidiosis with scleral melt
Pushpa Jacob, Jeyanth S Rose, Abhishek Hoshing, Geeta Chacko
May-June 2011, 59(3):251-253
DOI:10.4103/0301-4738.81046  PMID:21586855
A 16 year old girl presented with irritation and watering of the right eye for 3 months. On examination, the superior perilimbal sclera was ectatic with incarcerated uveal tissue covered by conjunctiva. The conjunctiva showed discreet, yellow white mucoid spots. Excision biopsy of the conjunctiva showed subepithelial spherules of sporangia containing numerous endospores, suggestive of rhinosporidiosis. Diathermy was applied to flatten the staphyloma. The ectatic area was covered with a corneal patch graft. The patient was started on prednisolone acetate eye drops and oral dapsone for 6 months. Corneal graft was well incorporated and conjunctivalized by 3 months. Since the graft was not seen within the palpebral aperture, there was good cosmetic result. The corneal graft had the added advantage of transparency which allowed visualization of the underlying tissue to diagnose early recurrence. There was no recurrence at 6 months.
  5,617 266 1
COMMUNITY EYE CARE
Ocular disorders in children with learning disabilities in special education schools of Pune, India
Parikshit Gogate, Freya Rao Soneji, Jitesh Kharat, Hemant Dulera, Madan Deshpande, Clare Gilbert, Parikshit Gogate, Freya Rao Soneji, Jitesh Kharat, Hemant Dulera, Madan Deshpande, Clare Gilbert
May-June 2011, 59(3):223-228
DOI:10.4103/0301-4738.81036  PMID:21586845
Aim: The aim was to study and treat ocular disorders in children with learning disabilities (cLDs) and explore associations with their perinatal history. Materials and Methods: cLDs attending 11 special schools were examined by a team consisting of an ophthalmologist, optometrist, and a social worker in 2007 and followed up in 2008. The students' intelligence quotient (IQ) and their medical histories were noted. Distant visual acuities were measured using Kay pictures or Snellen's tumbling E chart and complete ocular examination was performed. Students were assessed at the pediatric ophthalmology unit and low vision center, if needed. Statistical analysis was done with SPSS and the Chi-square test for ordinal data. Results: A total of 664 students were examined, 526 of whom were <16 years of age; 323 (61.4%) were male. A total of 326 (60%) had moderate-to-severe learning disabilities (IQs <50), and the mean IQ was 45.4. Two hundred and thirty-eight (45.3%) had ocular disorder; 143 (27.3%) had an uncorrected refractive error, followed by strabismus in 83 (15.8%), nystagmus in 36 (6.8%), optic atrophy in 34 (6.5%), and congenital anomalies in 13 (2.5%), 103 children had more than one abnormality. Only 12 of the 143 students with refractive errors were using spectacles. A total of 132 (48.7%) children with a history of perinatal insult had ocular problems. Ocular disorders were also common in those with a history of epilepsy, Down's syndrome, and cerebral palsy. Conclusion: Nearly half the cLDs in this study had ocular disorders and one-fourth had their vision improved.
  5,095 438 15
ORIGINAL ARTICLES
Visual recovery and predictors of visual prognosis after managing traumatic cataracts in 555 patients
Mehul Shah, Shreya Shah, Shashank Shah, Vinay Prasad, Avadh Parikh, Mehul Shah, Shreya Shah, Shashank Shah, Vinay Prasad, Avadh Parikh
May-June 2011, 59(3):217-222
DOI:10.4103/0301-4738.81043  PMID:21586844
The aim was to evaluate the visual recovery after managing traumatic cataracts and determine the predictors of a better visual prognosis. This was a prospective study. We enrolled patients with specific inclusion criteria, examined their eyes to review the comorbidities due to trauma, performed surgery for traumatic cataracts, and implanted lenses. The patients were reexamined 6 weeks postoperatively. We divided the cases of traumatic cataract into two groups, the "open globe" (Group 1) and "closed globe" (Group 2) groups, according to the ocular trauma based on the Birmingham Eye Trauma Terminology System (BETTS) and compared the determinants of visual acuity. Our cohort of 555 eyes with traumatic cataracts included 394 eyes in Group 1 and 161 in Group 2. Six weeks postoperatively, the visual acuity in the operated eye was >20/60 in 193 (48%) and 49 (29%) eyes in Groups 1 and 2, respectively (P = 0.002, ANOVA). At follow-up, >20/60 vision was significantly higher in Group 1 than in Group 2 (OR = 1.61; 95% CI, 0.85-3.02). Overall 242 (43.5%) eyes gained a final visual acuity of >20/60. Open globe injury has a favorable prognosis for satisfactory (>20/60) visual recovery after the management of traumatic cataracts.
  4,618 491 16
LETTERS TO THE EDITOR
Intravitreal bevacizumab in choroidal neovascularization associated with Best's vitelliform dystrophy
Subrata Mandal, Subijay Sinha, Pradeep Venkatesh, Nagender Vashisht
May-June 2011, 59(3):262-263
DOI:10.4103/0301-4738.81034  PMID:21586863
  4,642 211 7
BRIEF COMMUNICATIONS
Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report
Jayanta Kumar Das, Jnanankar Medhi, Ranjay Chakravarty, Ronel Soibam, Jayanta Kumar Das, Jnanankar Medhi, Ranjay Chakravarty, Ronel Soibam
May-June 2011, 59(3):231-233
DOI:10.4103/0301-4738.81039  PMID:21586847
An 18-year-old woman was referred with late sequelae of chloroquine-induced Steven-Johnson syndrome. At the time of presentation, the symblepharon was involving the upper lids to almost the whole of the cornea, and part of the lower bulbar conjunctiva with the lower lid bilaterally. Other ocular examinations were not possible due to the symblepharon. B-scan ultrasonography revealed acoustically clear vitreous, normal chorioretinal thickness, and normal optic nerve head, with an attached retina. Conjunctivo-corneal adhesion released by superficial lamellar dissection of the cornea. Ocular surface reconstruction was carried out with a buccal mucous membrane. A bandage contact lens was placed over the cornea followed by the symblepharon ring to prevent further adhesion. The mucosal graft was well taken up along with corneal re-epithelization. Best corrected visual acuity of 20/120 in both sides after 1 month and 20/80 after 3 months was achieved and maintained till the 2.5-year follow-up.
  4,261 340 6
ORIGINAL ARTICLES
Microalbuminuria and low hemoglobin as risk factors for the occurrence and increasing severity of diabetic retinopathy
VK Ajoy Mohan, Suneetha Nithyanandam, Jyothi Idiculla
May-June 2011, 59(3):207-210
DOI:10.4103/0301-4738.81029  PMID:21586841
Aim: To assess the influence of urinary microalbuminuria and hemoglobin concentration on the occurrence and severity of diabetic retinopathy (DR), clinically significant macular edema (CSME) and hard exudate formation. Materials and Methods: In this prospective cross-sectional study carried out over a period of 2 years, type 2 diabetic patients seeking ocular evaluation for DR were assessed for presence and severity of DR, presence of hard exudates and CSME. Retinal findings were correlated to severity of microalbuminuria, hemoglobin concentration and other systemic risk factors using linear regression analysis. Results: Three hundred and six patients were included in the study. DR of any grade was seen in 132 (43%) patients, hard exudate formation in 93/306 (30.4%) patients, CSME in 50/306 (16.3%) patients and proliferative DR in 26/306 (8.5%) patients. Duration of diabetes (P < 0.001), microalbuminuria (P < 0.001) and low hemoglobin (P = 0.001) were found to be highly significant risk factors for the development and increasing severity of DR as well as for CSME and hard exudate formation. Conclusion: Microalbuminuria and low hemoglobin are strong predictors for DR, CSME and hard exudate formation in type 2 diabetics even after correcting for duration of diabetes and other systemic risk factors. Although not directly involved in the pathogenesis, microalbuminuria can help in identifying patients at risk for more severe diabetic eye disease. Microalbuminuria warrants intensive monitoring of both retinal and renal status. The hemoglobin levels should be monitored regularly in diabetic patients to detect and treat anemia, thereby reducing one risk factor for DR.
  3,945 603 20
Ahmed glaucoma valve in post-penetrating-keratoplasty glaucoma: A critically evaluated prospective clinical study
Anita Panda, Vadivelu Jaya Prakash, Tanuj Dada, Anoop Kishore Gupta, Sudarshan Khokhar, Murugesan Vanathi
May-June 2011, 59(3):185-189
DOI:10.4103/0301-4738.81021  PMID:21586837
Aim: The aim was to evaluate the outcome of Ahmed glaucoma valve (AGV) in post-penetrating-keratoplasty glaucoma (PKPG). Materials and Methods: In this prospective study, 20 eyes of 20 adult patients with post-PKPG with intraocular pressure (IOP) >21 mmHg, on two or more antiglaucoma medications, underwent AG (model FP7) implantation and were followed up for a minimum of 6 months. Absolute success was defined as 5 < IOP < 21 mmHg and qualified success as 5 < IOP < 21 mmHg with medications or minor procedures. Results: The mean IOP decreased from 42.95 ± 10.24 to 17.69 ± 3.64 mmHg (P < 0.001) and the use of medications dropped from 2.92 to 0.39 (P < 0.001) after AGV implantation. The absolute success was achieved in 11 eyes and qualified success in 9. There was no significant change in best corrected visual acuity, graft clarity, or graft thickness. Six device-related complications occurred after AGV implantations which were successfully managed with medical or minor surgical therapy. Conclusions: Postkeratoplasty refractory glaucoma managed by AGV implantation revealed a satisfactory outcome up to 6 months of follow-up.
  3,792 716 6
BRIEF COMMUNICATIONS
Frosted branch angiitis, neuroretinitis as initial ocular manifestation in Behçet disease
Abdullah Al-Mujaini, Upender K Wali
May-June 2011, 59(3):240-241
DOI:10.4103/0301-4738.81048  PMID:21586851
Behçet disease is an idiopathic, multisystem disorder characterized by recurrent episodes of orogenital ulceration and vasculitis of the veins and arteries of all calibers. Ocular involvement may affect the conjunctiva, sclera, uveal tract, vitreous, blood vessels, and retina. Many theories have pointed toward an autoimmune response behind its pathogenesis, which may be triggered by exposure to an infectious agent. Frosted branch angiitis is characterized by vascular inflammation, sheathing, retinal edema, and retinal hemorrhages. The disease may be idiopathic in a majority of the cases or may be associated with ocular and systemic pathology. Association between Behηet disease, Frosted branch angiitis, and neuroretinitis is not reported in literature. This uncommon combination reflects the varied systemic and ocular manifestations in Behηet disease, especially in patients who are not diagnosed and treated in time. We hereby report a case of bilateral frosted branch angiitis and neuroretinitis in a young male from Middle-east, suffering from Behçet disease.
  4,202 282 15
Intravitreal bevacizumab (avastin) for circumscribed choroidal hemangioma
Subrata Mandal, Prashant Naithani, Pradeep Venkatesh, SatPal Garg
May-June 2011, 59(3):248-251
DOI:10.4103/0301-4738.81051  PMID:21586854
Circumscribed choroidal hemangiomas are rare ophthalmic entities that cause diminution in vision due to accumulation of subretinal and/or intraretinal fluid in the macular area. Various treatment options ranging from conventional laser to photodynamic therapy have been employed to destroy the tumor and reduce the exudation; however, either the inability to penetrate through the exudative fluid or the collateral retinal damage induced by these treatment modalities make them unsuitable for lesions within the macula. We evaluated the role of intravitreal bevacizumab, a pan-vascular endothelial growth factor (VEGF) inhibitor, in reducing the sub- and intraretinal fluid in three patients with circumscribed choroidal hemangiomas. All the patients had complete resolution of the serous retinal detachment that was maintained till at least 12 months after the first injection. Intravitreal bevacizumab may be used in combination with thermal laser or photodynamic therapy in treating circumscribed choroidal hemangiomas with subretinal fluid.
  4,124 295 12
Extrusion of hydrogel exoplant into upper eyelid 16 years after a scleral buckle procedure
Chirag P Shah, Sunir J Garg, Robert B Penne
May-June 2011, 59(3):238-239
DOI:10.4103/0301-4738.81047  PMID:21586850
Sixteen years after scleral buckle surgery with a hydrogel episcleral exoplant, a 43-year-old woman presented with progressive binocular diplopia, ptosis, and an expanding mass in her upper eyelid. She underwent surgical removal of the hydrogel exoplant through an anterior approach. The exoplant proved to be friable, fragmented, and encapsulated in a fibrous tissue; the exoplant was removed in its entirety. Postoperatively, the eyelid mass resolved, while her diplopia and ptosis improved slightly.
  4,151 176 5
Photodynamic monotherapy or combination treatment with intravitreal triamcinolone acetonide, bevacizumab or ranibizumab for choroidal neovascularization associated with pathological myopia
Pukhraj Rishi, Ekta Rishi, Anusha Venkataraman, Lingam Gopal, Tarun Sharma, Muna Bhende, Dhanashree Ratra, Pratik Ranjan Sen, Parveen Sen
May-June 2011, 59(3):242-246
DOI:10.4103/0301-4738.81049  PMID:21586852
This retrospective, interventional case series analyses treatment outcomes in eyes with choroidal neovascularization (CNV) secondary to pathological myopia, managed with photodynamic therapy, (PDT), (Group 1, N = 11), PDT and intravitreal triamcinolone acetonide (4 mg/0.1ml) (Group 2, N = 3), PDT and intravitreal anti-vascular endothelial growth factor (anti-VEGF) bevacizumab 1.25 mg/0.05 ml, ranibizumab 0.5 mg/0.05 ml and reduced-fluence PDT and intravitreal ranibizumab 0.5 mg/0.05 ml (Group 3, N=12). All the patients underwent PDT. Intravitreal injections were repeated as required. SPSS 14 software was used to evaluate the data. Wilcoxon signed ranks test was used to evaluate pre- and post-treatment vision. The Kruskal-Wallis test was used for comparison between the groups. All the groups were statistically comparable. All the eyes showed complete regression of CNV, with a minimum follow-up of six months. All groups had visual improvement; significantly in Group 3 ( p = 0.003). Combination PDT with anti-VEGF agents appeared to be efficacious in eyes with myopic CNV. However, a larger study with a longer follow-up is required to validate these results.
  3,482 287 5
LETTERS TO THE EDITOR
Excision of post small incision cataract surgery conjunctival inclusion cyst
Shreya Thatte, Lalita Gupta
May-June 2011, 59(3):257-259
DOI:10.4103/0301-4738.81028  PMID:21586859
  3,461 192 1
ORIGINAL ARTICLES
Objective structured clinical examination for undergraduates: Is it a feasible approach to standardized assessment in India?
Kavita R Bhatnagar, Vivek A Saoji, Amitav A Banerjee
May-June 2011, 59(3):211-214
DOI:10.4103/0301-4738.81032  PMID:21586842
Background: There has been a growing concern among medical educators about the quality of medical graduates trained in various medical colleges in our country. Data based on the faculty and student perceptions of undergraduate curriculum indicate a need for laying more stress on practical skills during their training and assessment. The Objective Structured Clinical Examination (OSCE) is a reliable and an established and effective multistation test for the assessment of practical skills in an objective and a transparent manner. The aim of this article is to sensitize universities, examiners, organizers, faculty, and students across India to OSCE. Materials and Methods: We designed an assessment based on 22-station OSCE and administered it to 67 students during their final year, integrating all the domains of learning, that is higher order cognitive domain, psychomotor domain, and affective domain. Data analysis was done using SPSS version 15. Results: The OSCE was feasible to conduct and had high perceived construct validity. There was a significant correlation between the station score and total examination score for 19 stations. The reliability of this OSCE was 0.778. Both students and faculty members expressed a high degree of satisfaction with the format. Conclusion: Integrating a range of modalities into an OSCE in ophthalmology appears to represent a valid and reliable method of examination. The biggest limitation with this format was the direct expenditure of time and energy of those organizing an OSCE; therefore, sustaining the motivation of faculty might pose a challenge.
  3,071 351 7
BRIEF COMMUNICATIONS
Eye-related visual hallucinations: Consider 'Charles Bonnet syndrome'
Nilgun Cinar, Sevki Sahin, Sibel Karsidag, Nilgun Cinar, Sevki Sahin, Sibel Karsidag
May-June 2011, 59(3):229-230
DOI:10.4103/0301-4738.81038  PMID:21586846
The Charles Bonnet Syndrome (CBS) is typically characterized by visual hallucinations in elderly people without cognitive defects. This article presents the case of an 80-year-old male patient with a one-year history of visual hallucinations, secondary to glaucoma, in both eyes. Neither a dopamine agonist nor cholinesterase inhibitor therapy improved his symptoms. In this case, the hallucinations were gradually improved after administration of a GABAergic drug, pregabalin, for diabetic polyneuropathy. Placebo-controlled clinical trials would be needed to support this effect of pregabalin, as suggested by this association.
  2,990 272 2
LETTERS TO THE EDITOR
Predominant exudative retinopathy in incontinentia pigmenti and clinical course after peripheral laser photocoagulation
Gaurav Sanghi, Mangat R Dogra, Munni Ray, Amod Gupta
May-June 2011, 59(3):255-256
DOI:10.4103/0301-4738.81022  PMID:21586856
  2,936 182 -
ORIGINAL ARTICLES
Comparison of anisometropes with and without amblyopia
Huban Atilla, Necile Erkam
May-June 2011, 59(3):215-216
DOI:10.4103/0301-4738.81035  PMID:21586843
Background: To compare binocular functions in amblyopic and non-amblyopic anisometropes and to investigate the possible associated factors for amblyopia development such as type of refractive error and initial age of refractive error correction. Materials and Methods: Prospectively anisometropic subjects with (n=42) and without amblyopia (n=33) were included in the study. Full ophthalmological examination including binocularity and motility was performed. Results: There was no statistically significant difference between the ages at the time of initial refractive error correction ( p0 =0.946). All of the anisometropes (100%) had fusion with Worth 4-dot test and Bagolini glasses. However 81% of amblyopic subjects had fusion with Worth 4 dot test and 88.1% had normal response with Bagolini glasses. Median stereopsis was 60 sec of arc in anisometropic subjects and 400 sec of arc in amblyopes. Conclusion: Our data support that, binocular functions are well developed in anisometropes without amblyopia and initial age at correction of refractive error has no primary effect on development of amblyopia.
  2,718 392 1
BRIEF COMMUNICATIONS
Massive retinal gliosis: An unusual case with immunohistochemical study
Sanjay D Deshmukh, Amrut V Ashturkar, Shridhar V Babanagare, Suvarna K Gokhale, Anand A Deshpande
May-June 2011, 59(3):246-248
DOI:10.4103/0301-4738.81050  PMID:21586853
Massive retinal gliosis (MRG) is a rare, benign intraocular condition that results from the proliferation of well-differentiated glial cells. Immunohistochemically, these cells show positivity for glial fibrillary acid protein (GFAP), neuron specific enolase (NSE), and S-100 protein. We encountered a case of a 45-year-old female with loss of vision in the left eye. She had a history of trauma to that eye two years ago. Enucleation was carried out, because malignancy was suspected due to retinal calcification. On the basis of light microscopy and immunohistochemistry (IHC) performed on the enucleated eye, it was diagnosed as massive retinal gliosis.
  2,840 223 2
ORIGINAL ARTICLES
Pupil cycle time and contrast sensitivity in type II diabetes mellitus patients: A pilot study
Hoyoung Lee, Youngkook Kim, Jongseok Park
May-June 2011, 59(3):201-205
DOI:10.4103/0301-4738.81027  PMID:21586840
Context: Pupil cycle time (PCT) has been widely used for examination of ocular diabetic autonomic neuropathy (DAN). Aims: The primary aim of this study was to evaluate the difference of contrast sensitivity according to PCT results, and the secondary aim was to determine the factors associated with PCT difference for type II diabetes patients. Settings and Design: A clinical pilot study that included a total of 60 eyes of 60 type II diabetes patients. Materials and Methods: We divided all patients into three groups according to PCT results. Group A and Group C were composed of patients who had upper one third PCT and lower one third PCT, respectively. We analyzed difference of age, diabetes duration, hypertension duration, mean best corrected visual acuity (BCVA), mean spherical equivalent (SE), HbA1C, glomerular filtration rate (GFR), stage of diabetic retinopathy, and Cardiac Autonomic Function Score (CAFS). Contrast sensitivity and decrease of visual acuity by glare were also estimated and analyzed for 28 eyes of 28 non-proliferative diabetic retinopathy (NPDR) patients. Group [NPDR] A and Group [NPDR] C were defined as those who had lower one third PCT and upper one third PCT, respectively. Statistical Analysis: Statistical analysis was done using SPSS 17.0 software. Results and Conclusions: Each group contained 20 eyes. Significant differences between Group A and Group C were observed in duration of diabetes and CAFS (P ≤ 0.001 and P < 0.001, respectively). Contrast sensitivity in Group [NPDR] A was significantly more than in Group [NPDR] C at all cpds (all P ≤ 0.001). We found that PCT can influence contrast sensitivity or glare in diabetes patients and also confirmed a significant correlation of PCT with CAFS and duration of diabetes.
  2,689 309 -
EDITORIAL
My strategic vision for the IJO of tomorrow
S Natarajan
May-June 2011, 59(3):183-184
DOI:10.4103/0301-4738.81020  PMID:21586836
  2,136 687 -
ORIGINAL ARTICLES
Intravitreal injection of methotrexate in an experimental rabbit model: Determination of pharmacokinetics
Ebru Bener Ozkan, Altan A Ozcan, Nazan Alparslan
May-June 2011, 59(3):197-200
DOI:10.4103/0301-4738.81026  PMID:21586839
Purpose: To investigate the pharmacokinetics of intravitreally administered methotrexate. Materials and Methods: Twenty-one New Zealand white rabbits were used in the study. The pharmacokinetics of intravitreally injected 800 μg/0.1 ml of methotrexate was investigated. Intravitreal concentration of the drug was measured at seven different times, in six eyes at each occasion, on a total of 42 eyes of 21 rabbits from a period of 30 minutes to 72 hours. Results: The volume of distribution was calculated as 1.33 ml following intravitreal injection of 800 μg methotrexate. Vitreous concentrations of the drug were found to be decreasing related to the specific mathematical equation; drug concentration= 1426.73 e -0.1182(time) and remained over effective dose by 81 hours with a half life of 5.9 hours. Conclusions: These findings evidenced those vitreous levels of methotrexate at various time intervals after 800 μg intravitreal injections which formulated a mathematical equation for calculation of vitreous level of the drug at each hour.
  2,439 271 5
BRIEF COMMUNICATIONS
Preserved scleral patch graft for unexpected extreme scleral thinning found at the scleral buckling procedure: A case report
Spela Stunf, Xhevat Lumi, Brigita Drnovšek-Olup, Spela Stunf, Xhevat Lumi, Brigita Drnovšek-Olup
May-June 2011, 59(3):235-238
DOI:10.4103/0301-4738.81045  PMID:21586849
Pre-existing scleral pathology is an important risk factor for globe rupture during scleral buckling procedures. We report here, the surgical management of an unexpected scleral pathology found at the scleral buckling procedure in a retinal detachment patient. A 77-year-old white female with retinal detachment underwent a scleral buckling procedure. The surgery was converted into a scleral graft procedure, as extreme scleral thinning was found intraoperatively. An alcohol-preserved donor sclera graft was used. The second surgery for definitive retinal alignment was performed two weeks later. The presented case of an unexpected scleral pathology in a retinal detachment patient was managed with a combination of scleral grafting and pars plana vitrectomy, without any major complications. The anatomical outcome was excellent and the scleral rupture was prevented; the visual outcome was satisfactory. A conversion of the scleral buckling procedure into a scleral graft procedure has proved to be safe and effective for unexpected scleral pathology.
  2,392 197 6
Subretinal lipid exudation associated with untreated choroidal melanoma
CK Minija, Mahesh P Shanmugam, CK Minija, Mahesh P Shanmugam
May-June 2011, 59(3):233-235
DOI:10.4103/0301-4738.81041  PMID:21586848
Subretinal lipid exudation in an untreated choroidal melanoma is very rare. It is seen following plaque radiotherapy in choroidal melanoma. There is only one case report of untreated choroidal melanoma with massive lipid exudation in a patient with metastatic hypernephroma. We report here a rare case of untreated choroidal melanoma with lipid exudation. Subretinal exudation that is rarely seen following plaque brachytherapy was noted at the borders of this untreated tumor. Lipid exudation partially resolved following brachytherapy.
  1,702 181 2
LETTERS TO THE EDITOR
Factors influencing the final visual outcome in open globe injuries
Shivcharan L Chandravanshi, Mahesh K Rathore, Eva R Tirkey, Uma S Tiwari
May-June 2011, 59(3):264-264
DOI:10.4103/0301-4738.81040  PMID:21586866
  1,411 239 -
Comment on: Is inclusion of Sabouraud dextrose agar essential for the laboratory diagnosis of fungal keratitis?
Ashok Sharma, Kanwar Mohan, Jagdish Chander, Suresh Sharma
May-June 2011, 59(3):260-261
DOI:10.4103/0301-4738.81031  PMID:21586861
  1,403 153 -
Prognostic factors for final vision outcome in patients with open globe injuries
Rupesh Agrawal
May-June 2011, 59(3):259-260
DOI:10.4103/0301-4738.81030  PMID:21586860
  1,306 200 1
Is inclusion of Sabouraud dextrose agar essential for the laboratory diagnosis of fungal keratitis?
Jayaraman Kaliamurthy, Philip A Thomas
May-June 2011, 59(3):263-264
DOI:10.4103/0301-4738.81037  PMID:21586864
  1,322 184 -
Residual triamcinolone acetonide at macular hole after vitreous surgery
Neha Goel, Anisha Seth, Vinod Kumar, Basudeb Ghosh
May-June 2011, 59(3):264-266
DOI:10.4103/0301-4738.81042  PMID:21586865
  1,331 163 1
Anti-vascular endothelial growth factor drugs in polypoidal choroidal vasculopathy
Jay Kumar Chhablani
May-June 2011, 59(3):256-257
DOI:10.4103/0301-4738.81025  PMID:21586857
  1,311 170 -
Hemi-central retinal artery occlusion in young adults
Amresh Chopdar
May-June 2011, 59(3):261-262
DOI:10.4103/0301-4738.81033  PMID:21586862
  1,260 183 1
Comment on rare complication of late posterior subluxation of a rollable intraocular lens after an uneventful microphacoemulsification cataract surgery
Hemang D Koppikar
May-June 2011, 59(3):256-256
DOI:10.4103/0301-4738.81024  PMID:21586858
  1,260 169 1
Alkalinization in peribulbar anesthesia for surgery on inflamed eye
Swati Zawar
May-June 2011, 59(3):266-266
DOI:10.4103/0301-4738.81044  PMID:21586867
  1,232 182 -