Figure 2: Nummular patches of retinal pigment epithelium (RPE) clumping in enhanced S-cone syndrome. Clinical picture in a 27-year-old girl who was presented with nyctalopia at 4 years of age (patient no. 12). (a and b) note the nummular patches of RPE atrophy (blue arrowheads) with surrounding punctate atrophic lesions in the mid-peripheral fundus. (c and d) Corresponding optical coherence tomography images showing minimal schitic spaces in the foveal region. This patient tested positive for NRL gene